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Protein A beads have been widely used for IgG purification. ’s Protein A (Cat# 6500) is a genetically engineered protein containing five IgG-binding regions of native Protein A. Maximum IgG...

K2503 | ToxOut™ Protein A Sepharose Antibody Purification Kit DataSheet

Protein G beads have been widely used for IgG purification. ’s Protein G (Cat# 6510) is a genetically engineered protein containing three IgG-binding regions of native Protein G. Maximum IgG...

Endotoxin is the lipopolysaccharide (LPS) complex located in the outer membrane of gram-negative bacteria. A single E.coli bacterium contains ~2 million LPS molecules (2 – 20 fg/cell). During...

Endotoxin is the lipopolysaccharide (LPS) complex located in the outer membrane of gram-negative bacteria. During experimental procedures, large amount of endotoxins are shed and can easily...

Endotoxin is the lipopolysaccharide (LPS) complex located in the outer membrane of gram-negative bacteria. During experimental procedures, large amount of endotoxins are shed and can easily...

Tozasertib inhibits Aurora kinases A, B and C with Ki values of 0.6, 18 and 4.6 nM, respectively. It also inhibits Flt-3 and Abl as well as their mutant forms.Tozasertib inhibits Aurora kinases A, B...

TP-0903 is a potent and selective AXL Inhibitor (IC₅₀ = 27 nM). TP-0903 induces massive apoptosis in CLL B cells with LD₅₀ values of nanomolar ranges. Treatment of cancer cells with TP-0903 reverses...

TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively. Displays anticancer activities.TP-3654 is a second-generation Pim kinase inhibitor...

3941 | TP2 Antibody DataSheet

3941BP | TP2 Blocking Peptide DataSheetAntibody Target: TP2Accession #: EAX08165.1Gene ID: 7015Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which...

Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which...

Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which...

Tissue plasminogen activator (PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which...

A potent and selective inhibitor of IκB kinase-2 (IKK-2) (IC₅₀ = 17.9 nM). Displays > 22-fold selectivity over IKK-1 and > 550-fold selectivity over other kinases and enzymes. TPCA-1 inhibits...

TPI1 (Triosephosphate isomerase) belongs to the triosephosphate isomerase family. TPI1 catalyzes the isomerization of glyceraldehydes 3-phosphate (G3P) and dihydroxy-acetone phosphate (DHAP) in...

5352 | TPO Antibody DataSheet

TPO (Thrombopoietin, also known as Mpl-ligand, MGDF) stimulates the proliferation and maturation of megakaryocytes and promotes increased circulating levels of platelets in vivo. TPO signals through...

TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels...

TPPU is a potent, brain-permeable, soluble epoxide hydrolase (sEH) inhibitor (IC50 values are 1.1 and 2.1 nM for murine and human receptor, respectively). Inhibits MAPK and NF-κB signaling, as well...

TPX-0005 is a potent ALK inhibitor. It inhibits WT ALK (IC50 1.01 nM) and mutant ALKs including ALK G1202R (IC₅₀ = 1.26 nM) and ALK L1196M (IC₅₀ = 1.08 nM). Moreover, TPX-0005 effectively inhibits...

3755 | TPX2 Antibody DataSheet

Trabectedin is a natural product originally isolated from the sea squirt, Ecteinascidia turbinata and is currently prepared synthetically. It interferes with transcription factors, DNA‐binding...

3561 | TRADD Antibody DataSheet

Antibody Target: TRADD Accession #: Q15628Gene ID: 8717Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 0.1%...

3563 | TRAF3 Antibody DataSheet

3563BP | TRAF3 Blocking Peptide DataSheetAntibody Target: TRAF3 Accession #: Gene ID: Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline...

3566 | TRAF6 Antibody DataSheet

Antibody Target: TRAF6 Accession #: Gene ID: Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1%...

3045 | TRAIL Antibody DataSheet

TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and...

Human TRAIL (TNF-Related Apoptosis Inducing Ligand), also called Apo2 Ligand (Apo2L), is a cytotoxic protein that activates rapid apoptosis in tumor cells, but not at normal cells. The recombinant...

K4262 | TRAIL/TNFSF10 Human Elisa Kit DataSheet

Cell-permeable. A potent angiogenesis inhibitor. Inhibits VEGF-induced angiogenetic activities. Displays anti-inflammatory and immunomodulatory effects by inhibiting lipid mediator and cytokine...

trans-ISRIB is an integrated stress response inhibitor. Potently reverses the effects of initiation factor 2α (eIF2α) phosphorylation (IC₅₀ = 5 nM). Enhances spatial and fear-associated learning in...

trans-Zeatin belongs to the plant hormone family known as ‘cytokinins’, which regulate cell division, development, and nutrient processing. The biosynthesis of cytokinins involves isoprenylation of...

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution...

7012 | Transferrin Antibody DataSheet

Transferrin is a monomeric glycoprotein found in plasma at an average concentration of 250 mg/100ml. The specific iron-binding protein in plasma, it has a role in the transportation and distribution...

K571 | Transglutaminase Activity Assay Kit Colorimetric DataSheet

K508 | Transglutaminase Inhibitor Screening Assay Kit DataSheet

A1001 | Transglutaminase-2 Antibody DataSheet

E4309 | Transthyretin TTR Human Elisa Kit DataSheet

E4310 | Transthyretin TTR Mouse Elisa Kit DataSheet

E4311 | Transthyretin TTR Rat Elisa Kit DataSheet

An inhibitor of monoamine oxidase (MAO) and prostacyclin synthase. Potently suppresses the enzymatic activity of Lysine-Specific Demethylase 1 (LSD1) (IC₅₀

KEY FEATURES & APPLICATIONS: • Water-soluble • Adds a 5-atom spacer arm (8.1 Å) to minimize steric hindrance • The spacer is cleavable at the disulfide bond with reducing agent, such as DTT,...

TRC051384 is an inducer of heat shock protein Hsp70. It reduces stroke-associated neuronal injury and increases survival in a rat model of transient ischemic stroke. It enhances Hsp72 expression in...

3564 | TreakR Antibody DataSheet

3841 | Anti-Trek1 Antibody DataSheet

3841BP | Trek1 Blocking Peptide DataSheetAntibody Target: Trek1 Accession #: AAV48996Gene ID: 16526Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Trelagliptin succinate (SYR-472) is a selective, long acting dipeptidyl peptidase-4 (DPP-4) inhibitor. An antidiabetic agent.Trelagliptin succinate (SYR-472) is a selective, long acting dipeptidyl...

TREM1 is a receptor belonging to the Ig super family that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and...

TREM2 is a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The protein functions in immune response and maybe involved in chronic...

Treponema Pallidum IgA, IgG, IgM Elisa Kit | E4675

E4676 | Treponema Pallidum IgG Elisa Kit DataSheet

E4677 | Treponema Pallidum IgM Elisa Kit DataSheet

Triamcinolone acetonide is an anti-inflammatory steroid that inhibits the IgE-dependent release of histamine. Like other corticosteroids, triamcinolone acetonide suppresses allergic, inflammatory,...

3-AP is a ribonucleotide reductase inhibitor and iron chelator with antitumor activity. At 5 μM it can enhance DU145, U251, and PSN1 tumor cell radiosensitivity in vitro, inhibiting DNA synthesis and...

6967 | TRIB1 Antibody DataSheet

Potent, reversible inhibitor of histone deacetylase. Mediates the activation of O6- methylguanine-DNA methyltransferase (MGMT). May be involved in cell cycle progression of several cell types,...

Cell-permeable. A synthetic tricyclic nucleoside which acts as a specific inhibitor of the Akt signaling pathway. It selectively inhibits the phosphorylation and activation of Akt1, -2 and -3 but...

Triclabendazole is a benzimidazole anthelminthic drug that binds to tubulin. TCBZ is used to treat liver fluke (Fasciola hepatica) infections in cattle and humans. It is effective against...

Ticlopidine hydrochloride is orally bioavailable drug inhibiting ADP induced platelet aggregation. It is selective P2Y12 receptor antagonist and might be better alternative in the prevention of...

Trifluorothymidine is an inhibitor of TS (thymidylate synthase). It is also a substrate used to study the specificity and kinetics of thymidine kinases. Acts as an anti-herpesvirus drug by blocking...

Triflupromazine is a member of a class of drugs called phenthiazines, which are dopamine D1/D2 receptor antagonists.Triflupromazine binds to the dopamine D1 and dopamine D2 receptors and inhibits...

K622 | Triglyceride Quantification Colorimetric/Fluorometric Kit DataSheet

Triglyceride Rat Elisa Kit | E4505

Trigonelline is a pyridine alkaloid found in various edible seeds and legumes, including coffee. It is a zwitterion formed by the methylation of the nitrogen atom of niacin (vitamin B3; nicotinic...

K7423 | Triiodothyronine T3 human Elisa Kit DataSheet

K7422 | Triiodothyronine T3 Mouse/Rat Elisa Kit DataSheet

Trilaciclib dihydrochloride is a CDK4/6 inhibitor which reduces chemotherapy-induced myelosuppression. It induces a G1 cell-cycle arrest in CDK4/6-dependent HS68 cells with an EC₅₀ of 30 nM. It is...

3241 | TRIM71 Antibody DataSheet

3241BP | TRIM71 Blocking Peptide DataSheetAntibody Target: TRIM71Accession #: Q2Q1W2Gene ID: 131405Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

Trimethoprim is an antibacterial agent, primarily active against most gram negative and gram positive aerobic bacteria. Inhibits dihydrofolate reductase. It is used clinically to treat urinary tract...

K670 | Triose Phosphate Isomerase TPI Activity Colorimetric Assay Kit DataSheet

3775 | TRIP1 Antibody DataSheet

A specific non-ATP competitive Aurora A kinase inhibitor. Does not significantly inhibit Aurora B kinase in mammalian cells. Reduces localization of pAurora A on spindle microtubules (MTs), affects...

Triptolide, a diterpenoid triepoxyde, a purified component of a traditional Chinese medicine, inhibits transcriptional activation of NF- κB and downregulates the expression of various NF-...

A 1 M solution of Tris HCl in water (pH 6.8).2106 | Tris-HCl (pH 6.8) DataSheetSort Name: Tris-HCl Solution (1 M, pH 6.8)Label Name: N/ATaglines: 1 M Tris-HCl solutionProduct Highlights: • Alternate...

A 1.5 M solution of Tris HCl in water (pH 8.8).2107 | Tris-HCl (pH 8.8) DataSheetSort Name: Tris-HCl Solution (1.5 M, pH 8.8)Label Name: N/ATaglines: 1.5 M Tris-HCl solutionProduct Highlights: •...

A solution (10%) of Triton® X-114 in de-ionized water.Triton ® X-114 (10%) Solution is a useful detergentB1015 | Triton ® X-114 (10%) Solution DataSheetAlternate Name/Synonyms:...

A non-ionic detergent useful for the isolation of membrane-bound proteins under non-denaturing conditions. Also useful for 2D-gel electrophoresis applications.Triton® X-100 Detergent is a non-ionic...

A 10% soultion of Triton X-100 in water.2104 | Triton® X-100 Solution (10% in H₂O) DataSheetSort Name: Triton® X-100 Solution (10% in H₂O)Label Name: N/ATaglines: 10% Triton X-100 solutionProduct...

A non-ionic detergent useful for the isolation of membrane-bound proteins under non-denaturing conditions. Also useful for 2D-electrophoresis applications.Triton® X-100, MegaPure™ Detergent, 10%...

A non-ionic detergent with a low cloud point (23 °C) assisting in protein solubilization with phase-partitioning of hydrophilic from amphiphilic proteins.Triton® X-114, MegaPure™ Detergent, 10%...

3194 | TrkA Antibody DataSheet

3194BP | TrkA Blocking Peptide DataSheetAntibody Target: TrkA Accession #: BAA34355Gene ID: 4914Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3593 | TrkB Antibody DataSheet

3593BP | TrkB Blocking Peptide DataSheetAntibody Target: TrkB Accession #: Q63604Gene ID: 25054Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate buffered...

TRKB is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. TRKB is the high affinity catalytic receptor for several "neurotrophins", which are small protein growth factors that...

An antidiabetic thiazolidinedione (TDZ) drug with anti-inflammatory and anti-tumor activities. A potent and selective PPARɣ agonist. The EC₅₀ values for transactivation of human and murine PPARɣ in a...

Troleandomycin is a macrolide antibiotic similar to erythromycin (Cat. No. 9619). Inhibits cytochrome P450 (IC50 = 0-5 μM), thus blocking CYP450-dependent drug oxidation. It binds to the 50S subunit...

Trolox is a cell-permeable, water-soluble derivative of vitamin E with potent antioxidant properties. It is commonly used as a standard or positive control in antioxidant assays. Trolox is used to...

Tropifexor (LJN452) is a highly potent, non-bile acid FXR (farnesoid X receptor) agonist with an EC₅₀ of 0.2 nM. Potentially useful for the treatment of Cholestatic Liver Diseases and Nonalcoholic...

Tropodithietic acid is a broad spectrum tropolone antibiotic with activity against both Gram-negative and Gram-positive bacteria. Displays cytotoxic effects on mammalian cell lines (neuronal N2a...

A1024 | Troponin T Monoclonal Antibody DataSheet

Trovafloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits the uncoiling of supercoiled DNA in bacteria by blocking the activity of topoisomerase IV (IC₅₀ = 3.02 µg/ml) and DNA gyrase...

Trovirdine is a potent inhibitor of HIV-1RT with IC₅₀ of 7 nM when employing heteropolymeric primer or template (oligo-DNA/ribosomal RNA) and dGTP as substrate.Trovirdine is a potent inhibitor of...