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3562 | TROY Polyclonal Antibody DataSheet

3562R | TROY/TAJ Antibody DataSheet

3562RBP | TROY/TAJ Blocking Peptide DataSheetAntibody Target: TROY/TAJ Accession #: Q9JLL3Gene ID: 29820Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

TRX818 is an orally bioavailable agent with potential antineoplastic and anti-vasculogenic mimicry (VM) activities. TRX-818, upon oral administration appears to induce cancer cell apoptosis and...

A water-soluble dye used for the dye exclusion test for cell viability to distinguish between viable and nonviable cells by seeping into nonviable cells with damaged plasma membranes causing them to...

K771 | Trypsin Activity Colorimetric Assay Kit DataSheet

A chromogenic trypsin substrate. Trypsin cleaves p-nitroanilide (pNA) releasing p-nitroanilne that can be quantified using a spectrophotometer or a microtiter plate reader at ~ 405 nm.Ac-GPK-pNA is a...

E4361 | Trypsin Try Human Elisa Kit DataSheet

E4362 | Trypsin Try Mouse Elisa Kit DataSheet

E4363 | Trypsin Try Rat Elisa Kit DataSheet

Trypsin hydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in...

Trypsin hydrolyzes peptides, amides, and ester bonds involving the carboxyl groups of L-arginine or L-lysine. Increased serum values of this enzyme and/or its zymogen (trypsinogen) have been found in...

Tryptanthrin is an alkaloid isolated from various plants and shows antimicrobial activity. It inhibits both 5-lipoxygenase and cyclooxygenase-2 with IC₅₀ values of 600 nM and 64 nM, respectively. It...

’s Tryptone is a pancreatic digest of casein and is used as a nitrogen source in culture media. It is capable of supporting growth of fastidious and non-fastidious microorganisms. The non-detectable...

K557 | Tryptophan Assay Kit Fluorometric DataSheet

3955 | TSC1 Antibody DataSheet

3955BP | TSC1 Blocking Peptide DataSheetAntibody Target: TSC1 Accession #: NP_075025Gene ID: 64930Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3962BP | TSC2 Blocking Peptide DataSheetAntibody Target: TSC2 Accession #: P49816. Gene ID: 24855Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Twisted Gastrulation Protein (TSG) is a secreted BMP binding protein structurally related to the BMP antagonists Chordin and Noggin. TSG can inhibit BMP activity by binding directly to BMP proteins,...

TSLP protein is a hemopoietic cytokine which signals throughout a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor & the Interleukin-7 receptor chain. TSLP...

3283 | TSP1 Antibody DataSheet

TTNPB is a highly potent retinoic acid receptor (RAR) agonist (EC₅₀ = 21 nM, 4.0 nM, and 2.4 nM for RARα, RARβ, and RARγ, respectively). Enhances reprogramming efficiency in chemically induced...

3551 | TTP Antibody DataSheet

3551BP | TTP Blocking Peptide DataSheetAntibody Target: TTPAccession #: P26651Gene ID: 7538Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

TTP-22 is a potent casein kinase 2 (CK2) inhibitor with an IC₅₀ value of 100 nM (Ki = 40 nM). It displays selectivity for CK2 over JNK3, ROCK1, and MET with no inhibitory effects towards these...

Tubacin (Tubulin acetylation inducer) is a highly potent, selective, reversible, and cell-permeable inhibitor of histone deacetylase 6 (HDAC6, IC₅₀ = 4 nM). Displays 1000-fold more selectivity for...

Cell-permeable. A potent and selective HDAC6 (histone deacetylase 6) inhibitor. Displays 1093-fold selectivity over HDAC1 (IC₅₀ values of 15 nM for HDAC6 vs 16.4 µM for HDAC1). Tubastatin A was...

3708 | Tubulin Antibody DataSheet

3708BP | Tubulin Blocking Peptide DataSheetAntibody Target: Tubulin Accession #: AAP36356.1Gene ID: 30584215Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3705 | TUCAN/CARD8 Antibody DataSheet

3705BP | TUCAN/CARD8 Blocking Peptide DataSheetAntibody Target: TUCAN/CARD8 Accession #: Q9Y2G2Gene ID: 22900Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

Tucatinib is an oral, potent, selective and ATP-competitive small-molecule inhibitor of Receptor tyrosine-protein kinase ErbB2 (also called HER2 or human epidermal growth factor receptor 2) with an...

Tucidinostat is an inhibitor of histone deacetylases (HDACs) with IC₅₀ values of 95 nM, 160 nM, 67 nM and 78 nM for HDAC1, HDAC2, HDAC3 and HDAC10 respectively. It shows potent antitumor activity. It...

Tudor domains are small protein structural motifs of about ~50 amino acids related to the “royal family” of methyl readers, which also includes chromo, MBT, PWWP, and Agenet-like domains. Tudor...

TUG-770 is a highly potent free fatty acid receptor 1 (FFA1/GPR40) agonist with EC₅₀ of 6 nM for hFFA1.The FFA1 increases glucose stimulated insulin secretion from pancreatic β-cells and efficiently...

TUG-891 is a potent GPR120 (free fatty acid receptor 4; FFAR4) agonist (pEC₅₀ values are 7.36 and 7.77 for human and mouse GPR120 respectively). Selective for GPR120 over free fatty acid receptors...

0.4 micron Immunobeads (Tumor Exosome Isolation, biofluids) M1032 | TumorExoPure™ 0.4 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids) DataSheet Sort Name: TumorExoPure™ 0...

1 micron Immunobeads (Tumor Exosome Isolation, biofluids)M1033 | TumorExoPure™ 1.0 micron Immunobeads (Tumor-derived Exosome Isolation, biofluids, 10 reactions) DataSheetSort Name: TumorExoPure™ 1.0...

Immunoplates for Exosome capture and quantification from human biofluids (plasma, serum, urine, saliva) and from human or mouse cell media. Transparent, white and black plates are available depending...

TumorExoPure™ Immunoplates (Exosome Isolation, plasma, fluorimetric assay) | M1018

TumorExoPure™ Immunoplates (Exosome Isolation, plasma, luminometric assay) | M1017

K1221 | TumorExoRNA™ Tumor-derived exosome immunocapture and RNA extraction kit 10 reactions DataSheet

From Streptomyces lysosuperificus. Provided as a mixture of tunicamycin A (C14), B (C15), C (C16) and D (C17) homologs in the fatty acid chain. Potent inhibitor of GlcNAc phosphotransferase which...

’s Human rhinovirus 3C protease (HRV3C Protease) is a cysteine protease that recognizes the cleavage site of Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro, commonly referred to as the PreScission Site. It cleaves...

’s TurboNuclease is a recombinant form of Serratia macescens extracellular endonuclease (encoded by the same gene of Benzonase) produced in E. coli using a proprietary process. This nonspecific...

’s TurboTEV Protease is a cysteine protease that recognizes the cleavage site of Glu-Xaa- Xaa-Y- Xaa-Gln-(Gly/Ser) and cleaves between Gln and Gly; the optimal sequence is Glu-Asn-Leu-Tyr-Phe-Gln-Ser...

TVB-2640 is an oral, selective fatty acid synthase (FASN) inhibitor. It reduces hepatic de novo lipogenesis in males with metabolic abnormalities. It is being evaluated in phase 2 clinical trials to...

TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively. TW-37 inhibits the growth of a broad range of cancer cells (such as...

TWEAKR belongs to the TNFR superfamily of transmembrane proteins and contains a cytoplasmic “death domain,” which can activated the cell’s apoptotic machinery. It is expressed in the spleen, thymus,...

Human TWEAK is a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. TWEAK, like many other members of the TNF family, is able to induce interleukin-8 synthesis in...

A 10% soultion of Tween 20 in water.2109 | Tween® 20 Solution (10% in H₂O) DataSheetSort Name: Tween® 20 Solution (10% in H₂O)Label Name: N/ATaglines: 10% Tween 20 solutionProduct Highlights: •...

A non-ionic detergent useful for the isolation of membrane-bound proteins under non-denaturing conditions.Tween® 20, MegaPure™ Detergent, 10% Solution is a non-ionic detergent useful for the...

A non-ionic detergent useful for the extraction of membrane-bound proteins as well as isolation of nuclei from mammalian cell lines.Tween® 80, MegaPure™ Detergent, 10% Solution is a non-ionic...

K1436 | Twort's Counterstain Kit DataSheet

TX1-85-1 is the first selective Her3 (ErbB3) ligand. TX1-85-1 forms a covalent bond with Cys721 located in the ATP-binding site of Her3.TX1-85-1 is the first selective Her3 (ErbB3) ligand. TX1-85-1...

7005BP | TXNRD1 Blocking Peptide DataSheetAntibody Target: TNXRD1Accession #: Q16881Gene ID: 7296Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in PBS (pH 7.2)...

TY-52156 is a novel S1P3 receptor antagonist (Ki = 110 nM). It preferentially inhibits the S1P-induced increase in intracellular calcium in Chinese hamster ovary cells expressing S1P3 over cell...

A 10% solution of the nonionic liquid surfactant Tyloxapol (Cat. No.1158) in waterA 10% solution of the nonionic liquid surfactant Tyloxapol (Cat. No.1158) in waterB1159 | Tyloxapol (10% ) solution...

Tyloxapol is a nonionic liquid polymer of the alkyl aryl polyether alcohol type that is used as a surfactant to aid liquefaction. Tyloxapol is used in the development of non-ionic surfactant-based...

A 10% solution of the nonionic surfactant Tyloxapol (Cat. No.1158) in water. Specially processed to remove the aldehydes and peroxides. Lacks the UV absorbance that causes interference in...

K742 | Tyrosinase Activity Assay Kit Colorimetric DataSheet

K575 | Tyrosinase Inhibitor Screening Kit Colorimetric DataSheet

K573 | Tyrosine Colorimetric Assay Kit DataSheet

3615 | Tyrosine Hydroxylase Antibody DataSheet

Selectively inhibits PDGF receptor auto-phosphorylation (IC₅₀ = 0.3-0.5 µM) and selectively inhibits PDGF dependent DNA synthesis. Potent inhibitor of human and porcine smooth muscle cell (SMC)...

Selectively inhibits EGF receptor auto-phosphorylation (IC₅₀ = 100 µM) and selectively inhibits DNA synthesis and cell growth; induces apoptosis. A JAK2 inhibitor. Blocks growth of leukemia cells in...

TZ9 is a triazine analogue inhibitor of human E2 ubiquitin-conjugating enzyme Rad6B/HHR6B. It docks to the Rad6B catalytic site. It inhibits Rad6B-induced histone H2A ubiquitination, downregulates...

U-104 is a ureido-sulfonamide inhibitor of transmembrane carbonic anhydrase IX (CAIX) (Ki = 45.1 nM) and XII (CAXII) (Ki = 4.5 nM). It displays weaker affinity for the cytosolic isoforms, CAI and...

U-18666A is a cell-permeable cholesterol trafficking inhibitor. It inhibits cholesterol transport from late endosomes/lysosomes to the endoplasmic reticulum (ER), but not cholesterol transport to the...

U-73122 is an Inhibitor of receptor-coupled phospholipase C-dependent processes in platelets and neutrophils via interfering with G protein-PLC interaction. A useful tool for probing the involvement...

U-73343 is a structural analog of U-73122 (Cat. No. B1887) that does not inhibit PLC, making it useful as a negative control for PLC inhibition. Cell-permeable.U-73343 is a structural analog of...

U-93631 is a GABAA receptor antagonist. U-93631 causes rapid decay of gamma-aminobutyric acid-induced chloride currents in recombinant rat gamma-aminobutyric acid type A receptors.U-93631 is a GABAA...

Potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC₅₀ values of 0.07 and 0.06 µM respectively) with little or no effect on the activities of PKC,...

Among ubiquitin-conjugating enzymes, the mammalian ubiquitin conjugating enzyme UbcH1, is unique in its ability to catalyze the in vitro synthesis of unanchored Lys48-linked poly-ubiquitin chains...

UbcH2 is the human homolog to the yeast DNA repair gene RAD6, which is induced by DNA damaging reagents. It has been shown to conjugate ubiquitin to histone H2A in an E3 dependent manner in vitro...

UbcH3 is a class II enzyme, homologous to Cdc34 from Saccharomyces cerevisiae, and is important in the control of cell cycle and DNA replication. UbcH3/Cdc34 in association with different E3...

UbcH5a is highly homologous to the S. cerevisiae Ubc4/5 family of E2 enzymes demonstrated to be essential for degradation of regulatory and abnormal proteins. UbcH5a, together with UbcH5b and UbcH5c,...

UbcH5b is highly homologous to the S. cerevisiae UbC4/5 family of E2 enzymes, demonstrated to be essential for degradation of regulatory and abnormal proteins. UbcH5b, together with UbcH5a and...

UbcH5c is highly homologous to the S. cerevisiae UbC4/5 family of E2 enzymes, demonstrated to be essential for degradation of regulatory and abnormal proteins. UbcH5c, together with UbcH5a and...

UBCS-039 is the first synthetic SIRT6 activator (EC50 = 38 μM); induces a time-dependent activation of autophagy in several human tumor cell lines. UBCS-039 induces deacetylation of SIRT6-targeted...

Ubiquitin-Aldehyde is a potent and specific inhibitor of deubiquitinating enzymes (DUBs) based on a C-terminal electrophilic Aldehyde group. Ub-Aldehyde can be used for activity profiling experiments...

Ubiquitin is a small, evolutionarily conserved eukaryotic protein that can be attached to a wide variety of intraCellular proteins including itself. Covalent attachment of ubiquitin to other proteins...

Prepared by the C-terminal derivatisation of ubiquitin with 7-amino-4-methylcoumarin. Acts as a useful and sensitive fluorogenic substrate for a wide range of deubiquitinylating enzymes (DUBs),...

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the...

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Apart from the established role of Ub in protein degradation, it...

Ubiquitin-rhodamine 110 is a quenched, fluorescent substrate for deubiquitylases, especially ubiquitin C-terminal hydrolases. Cleavage of the amide bond between the C-terminal glycine of ubiquitin...

Post-translational modification of proteins by ubiquitin (Ub) is a key regulatory process that impacts almost all cellular functions. Ubiquitylation occurs through isopeptide linkage between the...

K484 | UCH-L1 Deubiquitinase Inhibitor Screening Kit DataSheet

K471 | UCH-L3 Deubiquitinase Inhibitor Screening Kit DataSheet

6130 | UCHL1 Antibody DataSheet

Uchl3, as known as ubiquitin carboxyl-terminal hydrolase isozyme L3, is a member of the peptidase C12 family of deubiquitinating enzymes. It is widely expressed with the highest levels being observed...

6129 | UCHL5 Antibody DataSheet

6637 | UCP1 Antibody DataSheet

UF 010 is class I HDAC inhibitor that displays >6- fold selectivity over other HDACs. It has an IC₅₀ value of 0.06, 0.1, and 1.5 μM for HDACs 3, 2, 1 and 8 respectively. In vitro experimental data...

K692 | UGT Activity Assay / Ligand Screening Kit Fluorometric DataSheet

6144 | UHRF1 Antibody DataSheet

6145 | UHRF2 Antibody DataSheet

Ubiquitin is a highly conserved 76-amino acid protein. It can be conjugated via its C-terminus to the amine groups of lysine residues on target proteins. This conjunction is referred to as...

UK-371804 is a potent urokinase-type plasminogen activator (uPA) inhibitor with a Ki of 10 nM. Displays 4000-fold selectivity vs tPA and 2700-fold vs plasmin.UK-371804 is a potent urokinase-type...

UK-5099 is a potent and specific inhibitor of MPC (mitochondrial pyruvate carrier) activity. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria with an IC₅₀ value of...