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Cell-permeable. An inhibitor of the VEGFR tyrosine kinases VEGFR-1 (Flt-1, IC₅₀ = 77 nM) and VEGFR-2 (FLK-1/KDR, IC₅₀ = 37 nM), with slightly higher potency against the latter. At higher...

K7211 | VCAM-1 human Elisa Kit DataSheet

K7212 | VCAM-1 mouse Elisa Kit DataSheet

6783 | VCAM-1/CD106 Antibody (Center) DataSheet

3756 | VCP Antibody DataSheet

3594 | VDAC/Porin Antibody DataSheet

3594BP | VDAC/Porin Blocking Peptide DataSheetAntibody Target: VDAC/Porin Accession #: P21796Gene ID: 7416Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50µg (0.5 mg/ml) in...

VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM.VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki/IC50 of 13 nM/26 nM.B1723 |...

VE-822 | 2840

5363 | VEGF Antibody DataSheet

K5363 | VEGF human Elisa Kit DataSheet

K5364 | VEGF mouse Elisa Kit DataSheet

K5365 | VEGF rat Elisa Kit DataSheet

5641 | VEGF-B Antibody DataSheet

VEGF-B, a member of the VEGF family, is a potent growth and angiogenic cytokine. It promotes DNA synthesis in endothelial cells, regulates angiogenesis and Vascular permeability, and inhibits...

5633 | VEGF-C Antibody DataSheet

The recombinant VEGF-C (Vascular Endothelial Growth Factor-C) is a 125 amino acid protein that lacks the N-terminal signal peptide (from T103 to R227 of Gene Bank U58111). Human VEGF-C exhibits about...

VEGF-C (Vascular Endothelial Growth Factor-C) is a 125 amino acid recombinant protein that lacks the N-terminal and C-terminal extensions and contains only the middle third VEGF homology domain.4634...

VEGF-C (Vascular Endothelial Growth Factor-C) is a 125 amino acid recombinant protein that lacks the N-terminal and C-terminal extensions and contains only the middle third VEGF homology domain.4635...

5643 | VEGF-D Antibody DataSheet

VEGF-D is most closely related to VEGF-C by virtue of the presence of N- and C-terminal extensions that are not found in other VEGF family members. In adult human tissues, VEGF-D mRNA is most...

Vascular Endothelial Growth factor-A (VEGF-A) was originally isolated from tumor cells and is produced by a wide variety of cell types. In addition to stimulating vascular growth and permeability,...

VEGF (Vascular Endothelial Growth Factor) is a secreted homodimeric protein, secreted by a variety of Vascularized tissues. VEGF stimulates endothelial cell growth, angiogenesis, and capillary...

VEGF (Vascular Endothelial Growth Factor) is a secreted homodimeric protein, secreted by a variety of Vascularized tissues. VEGF stimulates endothelial cell growth, angiogenesis, and capillary...

VEGF (Vascular Endothelial Growth Factor) is a homodimeric protein secreted by a variety of Vascularized tissues. VEGF stimulates endothelial cell growth, angiogenesis, and capillary permeability...

Recombinant rat VEGF (Vascular Endothelial Growth Factor) is a double, non-glycosylated, polypeptide containing 164 amino acids and having a molecular mass of 38.4 kDa.4365 | VEGF165 rat recombinant...

5364R | VEGFAntibody DataSheet

VEGFR-2 and tubulin inhibitor inhibits polymerization of tubulin with an IC₅₀ of 1.1 μM. It inhibits the receptor tyrosine kinase VEGFR-2 in vitro and VEGFR-2 in cells with an IC₅₀ of 0.21 μM and 0...

VEGFR-2 inhibitor is a potent inhibitor of Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase (VEGFR-2). It shows 79% inhibition in the murine matrigel model for vascular permeability at...

VEGFR-2 has a lower affinity for VEGF than the Flt-1 receptor, but a higher signaling activity. Mitogenic activity in endothelial cells is mainly mediated by VEGFR-2 leading to their proliferation...

VEGI (Vascular Endothelial Growth Inhibitor) is a member of the tumor necrosis factor family. VEGI is predominantly an endothelial cell-specific gene, and recombinant VEGI is a potent inhibitor of...

Velpatasvir (formerly GS-5816) is a novel NS5A inhibitor that has potent in vitro anti-HCV activity across all genotypes at the picomolar level.Velpatasvir (formerly GS-5816) is a novel NS5A...

Venlafaxine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and weak inhibitor of dopamine reuptake. It displays no significant activity for muscarinic, histaminergic, or α-1...

3286 | VENTX Antibody DataSheet

3286BP | VENTX Blocking Peptide DataSheetAntibody Target: VENTXAccession #: O95231 Gene ID: 27287Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

VER-155008 is a potent heat shock protein 70 (Hsp70) inhibitor (IC₅₀ = 0.5 μM). Inhibits cell proliferation of multiple human tumor cell lines in vitro. Also binds Hsc70 and Grp78 and displays...

Verapamil is a L-type Calcium channel blocker. It has both peripheral and coronary vasodilator effects (IC₅₀ = 0.38 μM in guinea pig aortic strip) and has been used to control hypertension, angina,...

Veratridine is a steroidal alkaloid. Voltage-gated Na⁺ channel opener. May be used to increase Na⁺ concentration in cardiomyocytes and in cultured sympathetic neurons.Veratridine is a steroidal...

Vericiguat (BAY10-21189), is a potent and orally active sGC (Soluble Guanylate Cyclase) stimulator. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is...

Verteporfin is a photosensitizer used during photodynamic therapy to eliminate abnormal blood vessels in the eye that are associated with conditions such as macular degeneration. More recently,...

Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7) agonist which has been developed as an anti-hepatitis B virus (HBV) agent.Vesatolimod (GS-9620) is a potent Toll-like receptor-7 (TLR-7)...

Vesnarinone is a novel inotropic agent that displays unique and complex mechanisms of action. It inhibits phosphodiesterase, thereby leading to increased intracellular calcium, and also affects...

VGX-1027(GIT27) is an orally active immunomodulatory agent and a isoxazole compound that exhibits various immunomodulatory properties; reduce the secretion of IL-1beta, TNF-alpha and IL-10 from...

Second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC₅₀ =0.46 nM and IC₉₀ =1~10 nM to HIV isolates (n=52).Vicriviroc...

Vidofludimus is a novel immunosuppressive drug that inhibits DHODH; inhibits IL-17 secretion in vitro independently of effects on lymphocyte proliferation.Vidofludimus is a novel immunosuppressive...

Vigabatrin (VGB) is a structural analogue of gamma-aminobutyric acid (GABA) that irreversibly inhibits GABA-transaminase (GABA-T). It inhibits the catabolism of GABA by GABA transaminase and...

An antidiabetic agent. A potent inhibitor of dipeptidyl peptidase IV (DPP IV), an enzyme that breaks down Glucagon-like peptide 1 (GLP-1). By delaying the degradation of GLP-1, vildagliptin extends...

6771 | Vimentin Antibody (CT) DataSheet

3634 | Vimentin Antibody DataSheet

3634BP | Vimentin Blocking Peptide DataSheetAntibody Target: Vimentin Accession #: P08670Gene ID: 7431Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in phosphate...

Vimentins are class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells. Vimentin is attached to the nucleus, endoplasmic reticulum, and mitochondria,...

A plant alkaloid that arrests the cell cycle in G2/M phase by blocking mitotic spindle formation. Inhibits normal microtubule assembly and causes aberrant tubulin polymerization. Blocks binding of...

Vincristine is a plant alkaloid isolated from Vinca Rosea that irreversibly blocks mitosis by binding to tubulin (Ki = 85 nM) and inhibiting tubulin polymerization. It arrests cell cycle in...

Vinflunine tartrate | B2208

A semi-synthetic vinca alkaloid that displays potent anti-mitotic and anti-tumor properties. Its main mechanism of action is thought to be inhibition of microtubule dynamics, which results in mitotic...

Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, displays multiple biological activities, including strong inhibition of Gram-positive pathogens. It...

Vipadenant is a selective adenosine receptor antagonist, with Kis of 1.3 nM and 68 nM for A2A and A1, respectively. Vipadenant also reverses haloperidol-induced hypolocomotion in mice and rats...

K1446 | Viral DNA extraction and purification kit DataSheet

’s Viral Transport Medium is formulated for viral research and diagnostics. It is used for the collection, transport, maintenance and culture of virus. Its unique formulation is negative for...

’s Viral Transport, Veal Infusion Medium is formulated for viral research and diagnostics. It is used for the collection, transport and culture of virus. Its unique formulation is negative for...

Viridicatumtoxin is a tetracycline antibiotic isolated from several species of Penicillium. It is a potent antibacterial agent with activity against S. aureus including MRSA and QRSA strains...

5908 | Visfatin Antibody DataSheet

K4907 | Visfatin human Elisa Assay Kit DataSheet

Visfatin exerts insulin-mimetic effects that are dose-dependent and quantitatively similar to those of insulin in stimulating muscle and adipocyte glucose transport, and in inhibiting hepatocyte...

Visfatin also called Pre-B Cell Colony Enhancing Factor, Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt, PBEF4908 | Visfatin mouse recombinant...

Nicotinamide phosphoribosyltransferase (NAMPT), also known as visfatin or pre-B-cell colony enhancing factor, is a protein that catalyzes the formation of nicotinamide mononucleotide as part of the...

K303 | VisionBlue™ Quick Cell Viability Fluorometric Assay Kit DataSheet

Vitamin A is an intermediate in retinol metabolism in animals. It is metabolized to retinoic acid, a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR). roles in...

E4638 | Vitamin B12 Vit-B12 Elisa Kit DataSheet

K4806 | Vitamin D3 human Elisa kit DataSheet

Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen...

VK3-OCH3 is a Vitamin K3 (Menadione) analog that displays potent antitumor activity. It has been shown to induce G2/M arrest and apoptosis in neuroblastoma cells with much less cytotoxicity towards...

VLX600 is a small molecule which is cytotoxic to quiescent cells in colon cancer cells with an IC₅₀ of 1-10 μM. VLX600 decreases mitochondrial oxidative phosphorylation and shows enhanced cytotoxic...

A vanadium complex that acts as a highly potent and specific inhibitor of Phosphatase and Tensin Homologue Deleted on Chromosome 10 (PTEN).VO-Ohpic is a vanadium complex that acts as a highly potent...

Voglibose is a competitive α-glucosidase inhibitor (IC₅₀ = 5.6 µM). It delays the absorption and digestion of dietary polysaccharides by reversibly inhibiting digestive enzymes such as maltase,...

Vonoprazan fumarate is a Potassium-competitive acid blocker (P-CAB) that inhibits gastric H⁺/K⁺ATPase (IC₅₀ = 17 nM) but does not inhibit porcine Na+/K+ ATPase activity when used at a concentration...

Vorapaxar (SCH-530348) is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM). Vorapaxar inhibits thrombin receptor-activating...

Voriconazole is a triazole antifungal agent that displays potent activity against Candida, Cryptococcus and Aspergillus species. Useful for treatment of serious, invasive fungal infections...

Vortioxetine hydrobromide is a multimodal serotonergic agent that inhibits 5-HT1A, 5-HT1B, 5-HT3A, 5-HT7 receptor and SERT with Ki values of 15 nM, 33 nM, 3.7 nM, 19 nM and 1.6 nM, respectively...

VR23 is a potent and selective inhibitor of trypsin-like proteasomes (IC₅₀ = 1 nmol/L), chymotrypsin-like proteasomes (IC₅₀ = 50-100 nmol/L), and caspase-like proteasomes (IC₅₀ = 3 μmol/L). The main...

VRT752271 is a reversible, ATP-competitive inhibitor of ERK1 and ERK2 kinases, with IC50 of

VS-5584 is a potent and selective PI3K/mTOR kinase inhibitor. It inhibits mTOR (IC₅₀ = 37 nM) and PI3K (IC₅₀s = 16, 68, 25, and 42 nM for the α, β, γ, and δ isoforms, respectively) without relevant...

E4553 | VTCN1 Human Elisa Kit DataSheet

VU-0364439 is a potent positive allosteric modulator (PAM) of mGluR-4 (metabotropic glutamate receptor) (EC₅₀ = 19.8 nM in vitro for human mGluR-4).VU-0364439 is a potent positive allosteric...

VU0155041 is a potent, positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC₅₀ = 798 and 693 nM at human and rat mGlu4 receptors respectively). Active in in vivo models of...

VU 0361737 is a selective, brain-permeable, positive allosteric modulator at mGlu4 receptors (EC₅₀ values are 240 and 110 nM at human and rat receptors respectively). Inactive at mGlu1, mGlu2, mGlu3,...

VUF 8430 is a high affinity agonist (pKi = 7.5) for the histamine H4 receptor (pEC₅₀= 7.3). It is a moderate affinity agonist for the H3 receptor and is inactive at H1 and H2 receptor.VUF 8430 is a...

VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-Regulated Kinase); antitumor agent.VX-11e is a potent, selective, and orally bioavailable inhibitor of...

VX-222 is a potent, non-nucleoside inhibitor of HCV polymerase (IC₅₀ = 0.94-1.2 μM). It is 15.3-fold less effective for mutant M423T, and 108-fold less effective for mutant I482L.VX-222 is a potent,...

VX-661, is CFTR modulator that is potentially useful for treatment of cystic fibrosis. VX-661 corrects F508del-CFTR trafficking and increases F508del-CFTR protein activity in vitro.VX-661, is CFTR...

A p38 MAP kinase inhibitor. VX-702 dose-dependently inhibited the production of IL-6, IL-1β and TNFα (IC₅₀ = 59, 122 and 99 ng/ml, respectively). Pre-incubation of platelets with VX-702 (1 µM)...

VX-745 is a potent and selective inhibitor of p38α (IC₅₀ = 10 nM). It displays 22-fold greater selectivity versus p38β and no inhibition of p38γ. Also blocks TNFα production in LPS-stimulated HWB in...

VX-765 is a prodrug of VRT-043198, a potent and selective inhibitor of interleukin-converting enzyme/caspase-1 subfamily caspases. VRT-043198 displays 100- to 10,000-fold selectivity against...

VX-809 is a novel CFTR corrector that modulates the folding and trafficking of CFTR protein. VX-809 stabilizes an N-terminal domain in CFTR that contains only MSD1 (membrane-spanning domain 1) and...

K1437 | Warthin-Starry Stain Kit DataSheet

The Wash Buffer is used for suspension of cells in ’s CaspGlow™ Caspase Staining Kits (Cat. Nos. K172, K180, K182, K183, K188, K189, K190, K193, K198, and K199). For using this buffer in caspase...

WAY-100635 is a potent 5-HT1A receptor agonist. Displays high affinity and efficacy at the dopamine D4 receptor (1,2,3).WAY-100635 is a potent 5-HT1A receptor agonist. Displays high affinity and...

WAY-170523 is a potent and selective inhibitor of MMP-13 (IC₅₀ = 17 nM). Inhibits MMP-9, TACE and MMP-1 only at higher concentrations (IC₅₀ values of 945, >1000 and >10,000 nM, respectively)...

WAY-265497 is a potent ATP-binding site-targeting inhibitor of Cdk4/D1 kinase activity with an IC₅₀ of 30 nM. It inhibits HCT116 and MCF-7 cancer cells with IC₅₀ values of 0.73 and 0.88 µM,...

WAY-316606 is a secreted Frizzled-Related Protein-1 (sFRP-1) inhibitor (IC₅₀ = 0.65 μM). It blocks sFRP-1 from interacting with Wnt and thus increases Wnt signaling.WAY-316606 is a secreted...