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- Product
- Qty in Cart
- Quantity
- Price
- Subtotal
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RU-521 | B2547
26
NULL322.00 - NULL731.00RU-521 (RU-320521) is a potent, selective cyclic GMP-AMP synthase (cGAS) inhibitor (Kd = 36.2 nM). RU-521 is active and selective in cellular assays of cyclic GMP-AMP synthase-mediated signaling and...26-B2547-GENNULL322.00 - NULL731.00 -
RU-58841 | B2325
26
NULL633.00A specific androgen receptor antagonist; displays dramatic effect on hair regrowth.RU-58841 is a specific androgen receptor antagonist; displays dramatic effect on hair regrowth.B2325 | RU-58841...26-B2325-GENNULL633.00 -
Rubella IgG Elisa Kit - E4666
26
NULL952.00E4666 | Rubella IgG Elisa Kit DataSheet26-E4666-100-GENNULL952.00 -
Rubella IgM Elisa Kit - E4667
26
NULL952.00E4667 | Rubella IgM Elisa Kit DataSheet26-E4667-100-GENNULL952.00 -
Rubratoxin A | B1239
26
NULL879.00Rubratoxin A is a mycotoxin and protein phosphatase 2A (PP2A) inhibitor. Does not inhibit PP1, PP2B, PTP1B, ALP and CIP. It causes suppression of tumor metastasis and reduction of primary tumor...26-B1239-GENNULL879.00 -
Rubusoside | B1574
26
NULL403.00 - NULL994.00Rubusoside (Rub) is a natural sweetener from the Chinese sweet tea plant (Rubus suavissimus). Rubusoside inhibits transport by both GLUT1 and GLUT5.Rubusoside (Rub) is a natural sweetener from the...26-B1574-GENNULL403.00 - NULL994.00 -
Runx1/AML1-ETO polyclonal antibody | 6829
26
NULL601.006829 | Runx1/AML1-ETO polyclonal antibody DataSheet26-6829-50-GENNULL601.00 -
NULL584.00
-
Ruthenium Red | 2490
26
NULL305.00Ruthenium red is an inhibitor of mitochondrial Ca²⁺ uniporter; also blocks cell membrane-located capsaicin-activated cation channels (IC₅₀ = 14 nM) and voltage-sensitive Ca²⁺ channels to inhibit...26-2490-GENNULL305.00 -
Ruxolitinib phosphate | B2631
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NULL339.00 - NULL667.00Ruxolitinib phosphate is the phosphate salt form of ruxolitinib, a potent Janus-associated kinase (JAK) inhibitor with potential antineoplastic and immunomodulating activities. Ruxolitinib...26-B2631-GENNULL339.00 - NULL667.00 -
Ruxolitinib, Free base | 2139
26
NULL420.00Ruxolitinib is a potent and selective Janus kinase (JAK) inhibitor with with IC₅₀'s of 2.7 and 4.5 nM for JAK1 and JAK2, respectively. Displays clinically significant activity in myelofibrosis...26-2139-GENNULL420.00 -
RVX-208 | 9408
26
NULL290.00RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.RVX-208 is a potent inhibitor of BET bromodomains. It...26-9408-GENNULL290.00 -
RWJ-67657 | B2098
26
NULL928.00RWJ-67657 is a potent inhibitor of the MAP kinases p38α and p38β (IC₅₀s = 1 and 11 µM, respectively, in vitro); inactive against p38γ and p38δ, as well as several other kinases. RWJ-67657 blocks the...26-B2098-GENNULL928.00 -
Ryanodine | 2489
26
NULL454.00 - NULL650.00Ryanodine is a naturally occurring poisonous alkaloid that acts as a potent inhibitor of Ca²⁺ release from sarcoplasmic reticulum (IC₅₀s = 10 and 2.8 nM in skeletal and cardiac muscle, respectively)...26-2489-GENNULL454.00 - NULL650.00 -
Ryuvidine | B1808
26
NULL322.00Ryuvidine is a potent inhibitor of SET domain-containing protein 8 (SETD8) (IC₅₀ = 0.5 µM) that suppresses monomethylation of H4K20 in vitro. It displays weak inhibiton against cyclin-dependent...26-B1808-GENNULL322.00 -
R³ IGF-1, human recombinant | 4216
26
NULL363.00 - NULL60,379.00IGF-I (insulin-like Growth Factor-I) is a polypeptide growth factor that stimulates the proliferation of a wide range of cell types including muscle, bone, and cartilage tissue. s recombinant human...26-4216-GENNULL363.00 - NULL60,379.00 -
S- Adenosylhomocysteine Antibody Clone # 301-10 | 6945
26
NULL437.006945 | S- Adenosylhomocysteine Antibody (Clone # 301-10) DataSheet26-6945-25-GENNULL437.00 -
S- Adenosylmethionine Antibody Clone # 118-18 | 6942
26
NULL454.006942 | S- Adenosylmethionine Antibody (Clone # 118-18) DataSheet26-6942-25-GENNULL454.00 -
S- Adenosylmethionine Antibody Clone # 118-6 | 6940
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NULL650.006940 | S- Adenosylmethionine Antibody (Clone # 118-6) DataSheet26-6940-25-GENNULL650.00 -
S- Adenosylmethionine Antibody Clone # 84-19 | 6943
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NULL454.006943 | S- Adenosylmethionine Antibody (Clone # 84-19) DataSheet26-6943-25-GENNULL454.00 -
S- Adenosylmethionine Antibody Clone # 84-3 | 6941
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NULL650.006941 | S- Adenosylmethionine Antibody (Clone # 84-3) DataSheet26-6941-25-GENNULL650.00 -
S- Adenosylmethionine Antibody | 6944
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NULL650.006944 | Anti-S-Adenosylmethionine Antibody DataSheet26-6944-25-GENNULL650.00 -
S-(5'-Adenosyl)-L-methionine chloride (hydrochloride) | B2826
26
NULL290.00 - NULL601.00SAM is a ubiquitous methyl donor. It is a cofactor for methyl transferases such as catechol O-methyltransferase (COMT) and DNA methyltransferase. Most of it is present in the liver, where 85% of all...26-B2826-GENNULL290.00 - NULL601.00 -
NULL329.00
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S-100 Blocking Peptide | 3958BP
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NULL339.003958BP | S-100 Blocking Peptide DataSheetAntibody Target: S-100Accession #: P23297Gene ID: 6271Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...26-3958BP-50-GENNULL339.00 -
S-100 Protein, Bovine Brain | P1275
26
NULL716.00Biological Significance: S-100 is a low molecular weight, cytoplasmic, calcium binding protein. It is traditionally found in the brain, heart and muscle tissue. S-100 has two subunits (alpha-chain...26-P1275-GENNULL716.00 -
S-Adenosyl-L-methionine disulfate tosylate | 2077
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NULL322.00 - NULL977.00A methyl donor and a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in...26-2077-GENNULL322.00 - NULL977.00 -
S-Adenosylhomocysteine SAH Elisa Kit | E4542
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NULL1,119.00S-Adenosylhomocysteine SAH Elisa Kit | E454226-E4542-100-GENNULL1,119.00 -
S-Adenosylmethionine SAM Elisa Kit - E4541
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NULL1,354.00E4541 | S-Adenosylmethionine SAM Elisa Kit DataSheet26-E4541-100-GENNULL1,354.00 -
S-adenosylmethionine synthetase (AdoMetS), Active, E. coli Recombinant | P1211
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NULL388.00 - NULL699.00S-Adenosylmethionine synthase, (AdoMetS), (E.C. 2.5.1.6) catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential...26-P1211-GENNULL388.00 - NULL699.00 -
NULL329.00
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S-Tag Blocking Peptide | 3990BP
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NULL339.003990BP | S-Tag Blocking Peptide DataSheetAntibody Target: S-tagAccession #: N/AGene ID: N/AAppearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...26-3990BP-50-GENNULL339.00 -
S0859 | 9425
26
NULL371.00 - NULL928.00S0859 is a selective high-affinity generic inhibitor of the Na⁺/HCO3- sodium bicarbonate co-transporter (NBC). S0859 does not inhibit Na⁺-H⁺ exchange (NHE). S0859 could be potentially important for...26-9425-GENNULL371.00 - NULL928.00 -
S100A8 Antibody Clone IMG48M7C7 | 6196
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NULL830.006196 | S100A8 Antibody (Clone I mg48M7C7) DataSheet26-6196-100-GENNULL830.00 -
S100B, human recombinant | P1035
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NULL354.00 - NULL994.00S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in...26-P1035-GENNULL354.00 - NULL994.00 -
S107 free base | B3354
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NULL445.00 - NULL1,225.00S107 free base | B3354Description: S107 is a Type 1 ryanodine receptor (RyR1) stabilizer that binds RyR1 and enhances the binding affinity of calstabin-1. The intracellular Ca2+ leak was...26-B3354-GENNULL445.00 - NULL1,225.00 -
S1RA (E-52862) | B3048
26
NULL282.00 - NULL576.00S1RA is a highly selective sigma-1 (σ1) receptor antagonist. It shows high affinity for σ1 receptors with Ki values of 17 nM and 23.5 nM for human and guinea pig σ1 receptors respectively but no...26-B3048-GENNULL282.00 - NULL576.00 -
S63845 | B1819
26
NULL724.00S63845 is a potent and selective small molecule MCL1 inhibitor with Ki < 1.2 nM. S63845 potently kills MCL1-dependent cancer cells, including multiple myeloma, leukaemia and lymphoma cells, by...26-B1819-GENNULL724.00 -
SA4503 dihydrochloride | B3046
26
NULL371.00 - NULL928.00SA4503 is a potent sigma-1 (σ1 receptor) agonist. It shows 100 fold higher affinity for σ1 than σ2 receptor with IC₅₀ values of 17.4 nM and 1784 nM against 200 nM (+)-pentazocine for binding σ...26-B3046-GENNULL371.00 - NULL928.00 -
SAA1 monkey, recombinant | 4332
26
NULL625.00 - NULL10,895.00SAA1 protein is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 (Serum amyloid A1) protein is produced mainly in...26-4332-GENNULL625.00 - NULL10,895.00 -
Safe Image Super™ DNA Stain | M1198
26
NULL461.00Safe Image Super™ DNA StainM1198 | Safe Image Super™ DNA Stain DataSheetSort Name: Safe Image Super™ DNA StainLabel Name: Safe Image Super™ DNA StainTaglines: Safe Image Super™ DNA StainProduct...26-M1198-GENNULL461.00 -
Safe Image™ Basic DNA Stain | M1193
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NULL461.00Safe Image™ Basic DNA StainM1193 | Safe Image™ Basic DNA Stain DataSheetSort Name: Safe Image™ Basic DNA StainLabel Name: Safe Image™ Basic DNA StainTaglines: Safe Image™ Basic DNA StainProduct...26-M1193-GENNULL461.00 -
Safe Image™ DNA Stain Pack | M1197
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NULL461.00Safe Image™ DNA Stain PackM1197 | Safe Image™ DNA Stain Pack DataSheetSort Name: Safe Image™ DNA Stain PackLabel Name: Safe Image™ DNA Stain PackTaglines: Safe Image™ DNA Stain PackProduct...26-M1197-GENNULL461.00 -
Safe Image™ Fire Red DNA Stain | M1199
26
NULL461.00Safe Image™ Fire Red DNA StainM1199 | Safe Image™ Fire Red DNA Stain DataSheetSort Name: Safe Image™ Fire Red DNA StainLabel Name: Safe Image™ Fire Red DNA StainTaglines: Safe Image™ Fire Red DNA...26-M1199-GENNULL461.00 -
Safe Image™ Green DNA Stain | M1194
26
NULL461.00Safe Image™ Green DNA StainM1194 | Safe Image™ Green DNA Stain DataSheetSort Name: Safe Image™ Green DNA StainLabel Name: Safe Image™ Green DNA StainTaglines: Safe Image™ Green DNA StainProduct...26-M1194-GENNULL461.00 -
Safe Image™ Red DNA Stain | M1195
26
NULL461.00Safe Image™ Red DNA StainM1195 | Safe Image™ Red DNA Stain DataSheetSort Name: Safe Image™ Red DNA StainLabel Name: Safe Image™ Red DNA StainTaglines: Safe Image™ Red DNA StainProduct Highlights:...26-M1195-GENNULL461.00 -
Safe Image™ White DNA Stain | M1196
26
NULL461.00Safe ImageTMWhite DNA StainM1196 | Safe Image™ White DNA Stain DataSheetSort Name: Safe Image™ White DNA StainLabel Name: Safe Image™ White DNA StainTaglines: Safe Image™ White DNA StainProduct...26-M1196-GENNULL461.00 -
Safinamide | B2022
26
NULL322.00 - NULL731.00Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide also acts as a voltage-dependent...26-B2022-GENNULL322.00 - NULL731.00 -
SAG Analog (cis-isomer) | 2194
26
NULL650.00A cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist.SAG Agonist is a cell-permeable, highly active, Sonic hedgehog (Shh) signaling agonist. Smoothened...26-2194-GENNULL650.00 -
SAG Analog (trans-isomer) | 2196
26
NULL650.00A cell-permeable, low toxicity, Sonic hedgehog (Shh) signaling agonist. Smoothened (Smo) agonist. Also acts as a potent activator of VEGF expression in vitro.SAG Agonist is a cell-permeable, low...26-2196-GENNULL650.00 -
SAHA | 1604
26
NULL343.00 - NULL707.00Potent, reversible inhibitor of histone deacetylase 1 (HDAC1) and 3 (HDAC3). Induces cell growth arrest at both G1 and G2 phases. Induces apoptosis.SAHA is a potent, reversible inhibitor of histone...26-1604-GENNULL343.00 - NULL707.00 -
SAHA-Bpyne | B2840
26
NULL454.00 - NULL667.00SAHA-BPyne is a SAHA derivative with a benzophenone crosslinker and an alkyne tag. It is a photoreactive “clickable“ probe. It is used to profile histone deacetylase (HDAC) activities in native...26-B2840-GENNULL454.00 - NULL667.00 -
NULL329.00
-
Salbutamol SALB Elisa Kit - K4209
26
NULL1,518.00K4209 | Salbutamol SALB Elisa Kit DataSheet26-K4209-100-GENNULL1,518.00 -
Salermide | 1873
26
NULL863.00Cell-permeable. Salermide is an inhibitor of SIRT1 and SIRT2. In vitro, Salermide has a stronger inhibitory effect on SIRT2 than on SIRT1. It induces massive apoptosis in tumor cells through...26-1873-GENNULL863.00 -
Salicylate Assay Kit Colorimetric - K494
26
NULL961.00K494 | Salicylate Assay Kit Colorimetric DataSheet26-K494-100-GENNULL961.00 -
Salinomycin Sodium | B1584
26
NULL667.00Salinomycin is a polyether ionophore antibiotic that has recently been identified as an antitumor drug for several types of cancer stem cell (CSC) treatments. Salinomycin inhibits the migration and...26-B1584-GENNULL667.00 -
Salirasib | B2097
26
NULL371.00 - NULL928.00Salirasib is a potent Inhibitor of active Ras proteins. It displaces active Ras from the plasma membrane; impairs downstream signaling and inhibits proliferation of endometrial carcinoma cells. Also...26-B2097-GENNULL371.00 - NULL928.00 -
NULL584.00
-
SALL1 Blocking Peptide | 3237BP
26
NULL339.003237BP | SALL1 Blocking Peptide DataSheetAntibody Target: SALL1Accession #: D3ZIF4 Gene ID: 307740Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...26-3237BP-50-GENNULL339.00 -
Salmonella Typhi IgG Elisa Kit - E4678
26
NULL1,158.00E4678 | Salmonella Typhi IgG Elisa Kit DataSheet26-E4678-100-GENNULL1,158.00 -
Salmonella Typhi IgM Elisa Kit - E4679
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NULL1,158.00E4679 | Salmonella Typhi IgM Elisa Kit DataSheet26-E4679-100-GENNULL1,158.00 -
Salubrinal | 1980
26
NULL396.00Cell-permeable. A selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Also protects cells from endoplasmic...26-1980-GENNULL396.00 -
Salvianolic acid B | B3102
26
NULL363.00 - NULL903.00Salvianolic acid B is an antioxidant and anti-inflammatory compound extracted from Salvia miltiorrhiza. It shows cardioprotective and chemopreventative properties. It shows high free radical...26-B3102-GENNULL363.00 - NULL903.00 -
Salvinorin B | B1923
26
NULL305.00Salvinorn B is a potent and selective κ-opioid DREADD (KORD) agonist (EC₅₀ = 11.8 nM). DREADDs are chemogenetic tools widely used to remotely control cellular signaling, neuronal activity, and...26-B1923-GENNULL305.00 -
Sanguinarine | B2946
26
NULL290.00 - NULL601.00Sanguinarine is a benzylisoquinoline alkaloid that inhibits PP2C and shows selectivity for PP2C over PP1, PP2A, and PP2B in vitro. It inhibits MKP-1 with an IC₅₀ of 10 μM and shows selectivity for...26-B2946-GENNULL290.00 - NULL601.00 -
SANT-1 | 1978
26
NULL297.00Cell-permeable. A potent inhibitor of Sonic hedgehog (Shh) signaling; high affinity antagonist of smoothened activity (Kd = 1.2 nM). Inhibits smoothened agonist effects with an IC₅₀of 20 nM in...26-1978-GENNULL297.00 -
SANT-2 | 1976
26
NULL290.00Cell-permeable. A potent antagonist of Hedgehog (Hh) signaling pathway. Antagonizes smoothened receptor activity (KD = 12 nM) and inhibits SAG (Cat. No. 1939-500,1000) activity. SANT-2 should be a...26-1976-GENNULL290.00 -
Sapacitabine | B2002
26
NULL552.00 - NULL1,649.00Sapacitabine is an orally bioavailable nucleoside analog prodrug that is potentially useful for treatment of hematologic malignancies and solid tumors. The active metabolite of sapacitabine, CNDAC...26-B2002-GENNULL552.00 - NULL1,649.00 -
Saquinavir mesylate | B1999
26
NULL322.00Saquinavir mesylate is a HIV protease inhibitor (Kis = 0.12 and < 0.1 nM for HIV-1 and HIV-2 protease, respectively) that displays antiviral activity with low cytotoxicity.Saquinavir mesylate is a...26-B1999-GENNULL322.00 -
SAR-125844 | B2510
26
NULL305.00 - NULL633.00SAR-125844 is a potent, selective, reversible and ATP-competitive c-MET inhibitor, with an IC₅₀ of 4.2 nM. Displays inhibition of MET autophosphorylation in cell-based assays. Upon intravenous...26-B2510-GENNULL305.00 - NULL633.00 -
SAR-131675 | B2592
26
NULL371.00 - NULL879.00SAR-131675 is a potent and specific VEGFR-3 inhibitor. It inhibits VEGFR-3 tyrosine kinase activity (IC₅₀ = 20 nmol/L) and VEGFR-3 autophosphorylation (IC₅₀ = 5 nmol/L) in HEK cells, respectively...26-B2592-GENNULL371.00 - NULL879.00 -
SAR-20347 | B1290
26
NULL994.00SAR-20347 is a novel specific dual inhibitor of JAK1 and tyrosine kinase 2 (TYK2), inhibiting JAK1- and/or TYK2-dependent signaling from the IL-12/IL-23, IL-22, and IFN-alpha receptors.SAR-20347 is a...26-B1290-GENNULL994.00 -
SAR-260301 | B1263
26
NULL420.00 - NULL1,124.00SAR260301 is a potent and selective Class I phosphatidylinositol-3-kinase-β (PI3K-β) specific inhibitor with an IC₅₀ of 52 nM for this isoform. SAR260301 displays improved physicochemical and in...26-B1263-GENNULL420.00 - NULL1,124.00 -
SAR-405 | B1286
26
NULL1,248.00SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with mTOR inhibition in tumor cells.SAR-405 is a potent and selective PIK3C3/Vps34 inhibitor that...26-B1286-GENNULL1,248.00 -
SAR-407899 free base | B335
26
NULL368.00 - NULL914.00SAR-407899 free base | B3356Description: SAR-407899 is a potent and selective Rho kinase (ROCK) inhibitor with potential antihypertensive activity. SAR-407899 is equipotent against human and...26-B3356-GENNULL368.00 - NULL914.00 -
Saracatinib (AZD0530) | 1582
26
NULL1,550.00AZD0530 is a dually active inhibitor of c-Src and Bcr-ABL, on bone resorption. AZD0530 inhibited tumor growth in a manner independent of dose and inhibited phosphorylation of focal adhesion kinase...26-1582-GENNULL1,550.00 -
Sarcosine Colorimetric/Fluorometric Assay Kit - K636
26
NULL830.00K636 | Sarcosine Colorimetric/Fluorometric Assay Kit DataSheet26-K636-100-GENNULL830.00 -
Sarcosine | B3116
26
NULL282.00 - NULL576.00Sarcosine is an intermediate in the metabolism of glycine. Sarcosine is an antagonist of glycine transporter-1 (GlyT1) with an IC₅₀ value of 91 μM. It has beneficial effects in schizophrenia...26-B3116-GENNULL282.00 - NULL576.00 -
Sardomozide Hydrochloride | B2566
26
NULL403.00 - NULL1,059.00Sardomozide Hydrochloride is a second-generation polyamine synthesis inhibitor, that inhibits the activity of the polyamine biosynthetic enzyme S-adenosylmethionine decarboxylase (SAMDC). Sardomozide...26-B2566-GENNULL403.00 - NULL1,059.00 -
Sarecycline hydrochloride | B2383
26
NULL1,395.00Sarecycline is a semi-synthetic tetracycline, narrow-spectrum antibiotic being developed for use as an oral once daily antibiotic treatment for patients suffering from moderate to severe acne...26-B2383-GENNULL1,395.00 -
Sarecycline | B3077
26
NULL331.00 - NULL773.00Sarecycline is a semi-synthetic tetracycline, narrow-spectrum antibiotic, being developed to treat patients suffering from moderate to severe acne vulgaris. Sarecycline is more active than...26-B3077-GENNULL331.00 - NULL773.00 -
SARS-CoV-2 Spike Protein Receptor Binding Domain, Recombinant | P1734
26
NULL748.00 - NULL912.00SARS-CoV is an enveloped, single and positive-stranded RNA virus. Cell entry of severe acute respiratory syndrome coronavirus (SARS-CoV) is mediated by the viral spike (S) protein. The spike (S)...26-P1734-GENNULL748.00 - NULL912.00 -
SATA | 2363
26
NULL339.00A protein modification reagent used to convert primary amine groups into protected sulfhydryls (-SH). The sulfhydryl is readily made available for use in subsequent reactions by treatment with...26-2363-GENNULL339.00 -
Sauchinone | 2312
26
NULL290.00Isolated from Saururus chinensis. Displays cytoprotective and antioxidant activities in cultured hepatocytes. Suppresses NF-kB p65 activity. Neuroprotective. Bone resorption/osteoclastogenesis...26-2312-GENNULL290.00 -
Savolitinib | B3006
26
NULL305.00 - NULL667.00Savolitinib is an inhibitor of cMET tyrosine kinase or hepatocyte growth factor receptor (HGFR). It potently inhibits the tyrosine kinase activity of recombinant cMET in vitro with an IC₅₀ value of 4...26-B3006-GENNULL305.00 - NULL667.00 -
Saxagliptin | 9528
26
NULL403.00 - NULL1,059.00Saxagliptin is hydroxyadamantyl compound that acts as a potent, selective and reversible dipeptidyl peptidase-4 (DPP-4) inhibitor (IC₅₀ = 26 nM). An anti-diabetic agent.Saxagliptin is...26-9528-GENNULL403.00 - NULL1,059.00 -
SB 202190 | 2493
26
NULL322.00 - NULL731.00SB 202190 is a highly selective, potent, cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC₅₀ values of 50 and 100 nM, respectively. At...26-2493-GENNULL322.00 - NULL731.00 -
SB 203580 | 1712
26
NULL314.00 - NULL690.00Cell-permeable. Selective inhibitor of p38 mitogen-activated protein kinase (MAP Kinase) (IC₅₀ values are 50 and 500 nM for SAPK2a/p38 and SAPK2b/p38β2 respectively). Displays 100-500-fold...26-1712-GENNULL314.00 - NULL690.00 -
SB 216763 | 1769
26
NULL322.00 - NULL690.00A potent, cell-permeable and ATP-competitive inhibitor of glycogen synthase kinase-3 (GSK-3) (Ki= 9 nM for GSK-3α). Has little activity against 24 other protein kinases (IC₅₀ > 10 μM). Stimulates...26-1769-GENNULL322.00 - NULL690.00 -
SB 939 | 2285
26
NULL290.00An orally available pan-histone deacetylase (HDAC) inhibitor binding all HDAC isozymes with similar affinity (Kis = 16-28 nM) with the exception of HDAC6 and 7 (Kis = 247 and 104 nM, respectively)...26-2285-GENNULL290.00 -
SB-204490 | B2507
26
NULL305.00 - NULL633.00SB-204490 is a potent and specific ATP citrate lyase (ACLY) inhibitor. Prodrug of SB-201076. Inhibits cholesterol and fatty acid synthesis in a dose-dependent manner in HepG2 cells.SB-204490 is a...26-B2507-GENNULL305.00 - NULL633.00 -
SB-225002 | B3282
26
NULL371.00 - NULL928.00SB-225002 is a potent and selective inhibitor of chemokine receptor CXCR2 with an IC50 of 22 nM for inhibiting interleukin IL-8 binding to CXCR2; displays > 150-fold selectivity over CXCR1 receptors...26-B3282-GENNULL371.00 - NULL928.00 -
SB-242235 | B2273
26
NULL879.00SB-242235 is a potent and selective p38 MAP kinase inhibitor (IC₅₀ = 1.0 uM).SB-242235 is a potent and selective p38 MAP kinase inhibitor (IC₅₀ = 1.0 uM).B2273 | SB-242235 DataSheetAlternate...26-B2273-GENNULL879.00 -
SB-265610 | B3283
26
NULL339.00SB-265610 is a potent and selective CXCR2 chemokine receptor antagonist (Kd = 2.5 nM). It does not bind to CXCR1). Inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in...26-B3283-GENNULL339.00 -
SB-297006 | B2589
26
NULL339.00 - NULL797.00SB-297006 is a C-C chemokine receptor-3 antagonist (CCR3; IC₅₀ = 39 nM).SB-297006 is a C-C chemokine receptor-3 antagonist (CCR3; IC₅₀ = 39 nM).B2589 | SB-297006 DataSheetAlternate Name/Synonyms:...26-B2589-GENNULL339.00 - NULL797.00 -
SB-415286 | B1954
26
NULL1,248.00SB-415286 is a potent, selective and ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (Ki = 31 nM for GSK-3α). Displays minimal activity against 24 other protein kinases (IC₅₀ > 10 μ M)...26-B1954-GENNULL1,248.00 -
SB-431542 | 1674
26
NULL363.00 - NULL781.00A potent and selective inhibitor of the TGF-β1 receptor ALK5 (IC₅₀ = 94 nM). It inhibits ALK4 only at higher concentrations (IC₅₀ = 140 nM). Suppresses renewal in embryonic and induced pluripotent...26-1674-GENNULL363.00 - NULL781.00 -
SB-525334 | 2880
26
NULL1,059.00SB-525334 is a potent and selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC₅₀ = 14.3 nM); displays 4-fold less potency against ALK4 (IC₅₀ = 58.5 nM) and inactive as...26-2880-GENNULL1,059.00 -
SB-590885 | B1708
26
NULL371.00 - NULL928.00SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity for B-Raf over c-Raf, no inhibition to other human kinases.SB590885 is a potent B-Raf inhibitor with Ki of 0.16...26-B1708-GENNULL371.00 - NULL928.00