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SSR128129E (SSR) is a potent small molecule, allosteric inhibitor of FGFR signaling. SSR binds to the extracellular part of the receptor and it does not compete with FGF for binding to FGFR but...

SSX2 belongs to the family of cancer/testis (CT) antigens with characteristic mRNA expression in normal testis and in cancer. This gene belongs to the family of highly homologous synovial sarcoma X...

ST3Gal1 catalyzes transfer of the sialic acid Neu5Ac from CMP-Neu5Ac (cytidine 5'-monophosphono-N-acetylneuraminic acid) to Gal1, 3GalNAc on glycoproteins or glycolipids in an 2, 3 linkage. It is a...

Alpha-N-acetylgalactosaminide -2,6-sialyltransferase 1 catalyzes the transfer of sialic acid N-acetylneuraminic acid (Neu5Ac) from cytidine 5'-monophosphono-N-acetylneuraminic acid (CMP-Neu5Ac) to...

STA-21 is a natural antibiotic that acts as a selective STAT3 inhibitor. It inhibits STAT3 by preventing its dimerization and DNA binding when used at concentrations of 20-30 μM. It blocks the growth...

K647 | Starch Colorimetric/Fluorometric Assay Kit DataSheet

Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha...

3133R | Stat1 Antibody DataSheet

3133RBP | Stat1 Blocking Peptide DataSheetAntibody Target: Stat1 Accession #: AAF20200Gene ID: 25124Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 μg (0.5 mg/ml) in phosphate...

3468R | Stat2 Antibody DataSheet

3468RBP | Stat2 Blocking Peptide DataSheetAntibody Target: Stat2 Accession #: CAE45713.1Gene ID: 6773Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

Cell-permeable. A potent and selective inhibitor of Stat3 SH2 domain:pTyr interactions; also disrupts the binding of Stat3 to the IL-6R/gp130 peptide, GpYLPQTVNH₂ and induces antitumor effects in...

3470RBP | Stat3 Blocking Peptide DataSheetAntibody Target: Stat3 Accession #: AAA19452.1Gene ID: 20848Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

K4201 | STAT3 Human Elisa Kit DataSheet

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the...

C188-9 is a potent STAT3 inhibitor that binds to STAT3 with high affinity (Kd of 4.7 nM). C188-9 has the ability to inhibit STAT3 binding to its pY-peptide ligand, to inhibit cytokine-stimulated...

Cell-permeable. A peptide-based inhibitor, PY*LKTK-mts (mts = membrane translocating sequence) that selectively inhibits constitutive and ligand-induced activation of Stat3 in vivo. Also suppresses...

3471R | Stat4 Antibody DataSheet

3471RBP | Stat4 Blocking Peptide DataSheetAntibody Target: Stat4 Accession #: NP_001012226Gene ID: 367264Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3472 | Stat5 Antibody DataSheet

3472BP | Stat5 Blocking Peptide DataSheetAntibody Target: Stat5 Accession #: P51692Gene ID: 6777Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

STAT5 Inhibitor suppresses STAT5 by targeting its SH2 domain (IC₅₀ = 47 µM against STAT5β SH2 domain EPO peptide binding activity). Comparatively, this compound displays reduced potency towards...

3473R | Stat6 Antibody DataSheet

3473RBP | Stat6 Blocking Peptide DataSheetAntibody Target: Stat6 Accession #: NP_001037715.1Gene ID: 362896Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Stattic is a small molecule that selectively inhibits STAT3 activation, dimerization, and nuclear translocation by preventing the binding of tyrosine-phosphorylated peptide motifs to the STAT3 SH2...

A cell-permeable analog of Staurosporine (Cat. No. 1048-010, 1) that primes embryonic stem cells (ESCs) for differentiation. Interacts with NME2 and inhibits its nuclear translocation. Increases the...

Potent inhibitor of protein kinase C and most other kinases, including tyrosine kinases. Inhibits topoisomerase II directly by blocking transfer of phosphodiester bonds from DNA to active site...

Stavudine is a nucleoside analog that acts as a reverse transcriptase inhibitor. Displays in vitro activity against HIV. An antiviral agent.Stavudine is a nucleoside analog that acts as a reverse...

K791 | StayBrite™ Highly Stable ATP Bioluminescence Assay Kit DataSheet

’s StayBrite Highly Stable Luciferase (rLucHS) is a genetically modified variant derived from the Luciferase of Diaphanes pectinealis (Chinese Firefly) endemic to Yunnan province, China. It has been...

K790 | StayBrite™ Highly Stable Luciferase/Luciferin Reagent DataSheet

K1435 | Steiner Stain Kit DataSheet

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing two small molecules useful for enhancing the reprogramming efficiency of human somatic cells to induced pluripotent stem...

A convenient, sterile-filtered cocktail solution (100X, in DMSO) containing four (4) small molecules useful for reprogramming of mouse fibroblasts into cardiac cells. The four products are: SB-431542...

FMM cocktail is a cocktail of three small molecules in DMSO. This media additive along with basic fibroblast growth factor (bFGF) and leukemia inhibitory factor (LIF), supports the continuous...

A convenient set containing three recombinant mouse growth factors including Stem Cell Factor (SCF), Flt3-ligand, and Thrombopoietin (TPO) that are commonly used for Stem Cell culture. CONTENTS: ...

A convenient set containing four recombinant human growth factors including Stem Cell Factor (SCF), Flt3-ligand, Interleukin 6 (IL-6) and Interleukin 3 (IL-3) that are commonly used for Hematopoietic...

A convenient set containing two recombinant human growth factors including epidermal growth factor (EGF) and Fibroblast Growth Factor 2 (FGF-2/FGF-basic) that are commonly used for Neural Stem Cell...

A convenient set containing four recombinant mouse growth factors including Stem Cell Factor (SCF), Flt3-ligand, Interleukin 6 (IL-6) and Interleukin 3 (IL-3) that are commonly used for Hematopoietic...

A convenient set containing two recombinant mouse growth factors including epidermal growth factor (EGF) and Fibroblast Growth Factor 2 (FGF-2/FGF-basic) that are commonly used for Neural Stem Cell...

A convenient set containing three recombinant mouse growth factors including Granulocyte Colony Stimulating Factor (G-CSF), Flt3-ligand, and Thrombopoietin (TPO) that are commonly used for Stem Cell...

StemBoost™ Reprogramming Cocktail ZAPK is a Small Molecule Cocktail of 4 modulators in DMSO solution that acts as an iN (induced neuron) conversion medium. This medium reliably boosts iN conversion...

StemBoost™ Neural Stem Cell Reprogramming Cocktail is a convenient, sterile-filtered cocktail solution (100X, in DMSO) containing eight (8) small molecules useful for reprogramming of fibroblasts...

StemBoost™ Neuronal Cell Induction Cocktail Set (100X), Sterile-Filtered is a convenient, sterile-filtered cocktail solution (100X, in DMSO) containing the following six small molecules: CHIR99021...

A convenient, sterile-filtered cocktail solution (10X, in DMSO) containing four (4) small molecules useful for reprogramming of mouse fibroblasts into functional neurons. The four products are:...

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing three small molecules useful to induce rapid and efficient neuronal differentiation of human pluripotent stem cells...

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing four small molecules useful for enhancing the reprogramming efficiency of human somatic cells to induced pluripotent stem...

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing four small molecules useful for enhancing the reprogramming efficiency of human somatic cells to induced pluripotent stem...

StemBoost™ Reprogramming Cocktail, 3i, is a convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing three small molecules useful for enhancing the reprogramming efficiency of mouse...

SLCD is a cocktail of 4 small molecule inhibitors in DMSO solution. This cocktail assists in efficiently reprogramming human fetal astrocytes into functional neurons. The cocktail (100X) solution...

SMC4 is a Small Molecule Cocktail of 4 inhibitors in DMSO solution. This media additive supports the derivation of hiPSCs (Human induced Pluripotent Stem Cells) in feeder or feeder-free culture...

StemBoost™ Reprogramming Cocktail, VCRFBI (100X), is a convenient, sterile-filtered cocktail solution (100X, in DMSO) for the generation of human neuronal cells from adult astrocytes. The cocktail...

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing two small molecules useful for inhibiting SMAD signaling. Can be used to accelerate human pluripotent stem cells (hPSCs)...

A convenient, sterile-filtered cocktail solution (1000X, in DMSO) containing four signaling inhibitors YPAC (Y-27632, a ROCK inhibitor, 10.0 mM; PD0325901, a MEK Inhibitor,1.0 mM; A83-01, a ALK5...

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells I | K3101

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells II | K3102

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells III | K3103

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells IV | K3104

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells V | K3105

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells VI | K3106

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells VII | K3107

StemFate-4 CFC/CFU Differentiation Assay Kit for Human Cells VIII | K3108

A cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs). Culture of HSCs with SR1 led to a 50-fold...

A cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of hematopoietic stem cells (HSCs). Culture of HSCs with SR1 led to a 50-fold...

Stevioside is an antidiabetic and antihyperglycaemic and antihypoglycaemic agent. Potentiates insulin secretion. Enhances acetyl-CoA carboxylase (ACC) gene expression. Increases insulin sensitivity...

STF-083010 is a potent Ire1 inhibitor. STF-083010 inhibits Ire1 endonuclease activity, without affecting its kinase activity, after endoplasmic reticulum stress. It blocks endogenous XBP1 mRNA...

STF-118804 is a potent and highly specific inhibitor of Nampt (nicotinamide phosphoribosyl transferase) (IC₅₀s = 3-6 nM) that prevents NAD⁺ synthesis from nicotinamide. It inhibits the viability of...

STF-31 is a potent glucose transporter 1 (GLUT1) inhibitor (IC₅₀ = ~ 1 µM). It induces necrosis in cancer cells that lack the von Hippel-Lindau tumor suppressor gene, which overexpress GLUT1...

STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity...

STIMA-1 (SH group-targeting compound that induces massive apoptosis) reactivates mutant p53. STIMA-1 can stimulate mutant p53 DNA binding in vitro and induce expression of p53 target proteins and...

STING-agonist-C11 is an agonist of the STING pathway, inducing IFN secretion from human cells. C11 activates the type I IFN response in a manner that requires the adaptor protein STING but does not...

STING AGONIST G10 is an indirect activator of STING-dependent signaling. Stimulates IRF-3-induced transcription and induces IFNα and IFNγ gene expression in human fibroblasts. STING AGONIST G10 is an...

STING Antagonist C-178 is a potent inhibitor of the signaling molecule STING in mouse cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91.STING...

H-151 is a potent antagonist of the signaling molecule STING in mouse and human cells. It covalently binds to Cys91 of STING preventing activation via blockade of palmitoylation at Cys91. It reduces...

STING inhibitor C-176 is a potent, small-molecule inhibitor of STING (stimulator of interferon genes) protein, that attenuates STING-associated autoinflammatory disease in mice. STING protein is a...

STK-321130（FLT3-IN-2）is a potent FLT3 inhibitor.STK-321130（FLT3-IN-2）is a potent FLT3 inhibitor.B2006 | STK-321130 DataSheetAlternate Name/Synonyms:...

Creasy identified a cDNA encoding STK3, which they called MST2. Sequence analysis indicated that the deduced 491-amino acid STK3 protein contains an N-terminal catalytic domain characteristic of STKs...

Tumor Necrosis Factor receptor type I (TNF-RI) is also referred as p60. The p60 form of the receptor is primarily expressed on epithelial cells. Recombinant Human soluble TNF receptor Type I...

STO-609 is a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinaseSTO-609 is a specific inhibitor of the Ca2+/calmodulin-dependent protein kinase kinaseB1609 | STO-609...

5397 | STOX1 Antibody (CT) DataSheet

3382 | STOX2 Antibody DataSheet

3382BP | STOX2 Blocking Peptide DataSheetAntibody Target: STOX2Accession #: D4A001Gene ID: 306459Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic “death domain,” which can activate the cell’s apoptotic machinery...

Human sTRAIL Receptor-2, also known as DR5 (Death Receptor-5), is a member of the TNF receptor family. The recombinant human sTRAIL Receptor-2 is a 14.9 kDa protein containing 133 amino acid residues...

Streptavidin is a non-glycosylated protein originally isolated from bacterium Streptomyces avidinii. With a very high affinity for biotin, it is widely used to bridge biotinylated probes and enzymes...

’s High Sensitivity Streptavidin plates (clear, 12x8-Well Strips), are ready-to-use biotin-binding microplates. Proprietary coating of the plates with highly pure streptavidin allows the user to...

Streptavidin, a protein from Streptomyces avidinii, is known to bind to biotin with very high affinity (dissociation constant 10-14 M). It has a tetrameric structure in which each molecule of...

E4272 | Streptomycin Elisa Kit DataSheet

An aminoglycoside antibiotic useful for inhibition of bacterial protein synthesis at the level of initiation inhibition. Streptomycin sulfate targets primarily Gram positive bacteria and...

An antitumor antibiotic. Acts as a DNA alkylating agent that enters cells exclusively via the GLUT2 glucose transport protein. Also acts as a diabetagen,and is especially toxic to pancreatic islet...

A specific, ATP-competitive small molecule inhibitor of the catalytic activity of Met. Displays selectivity for Met enzyme versus a panel of other tyrosine kinases with the following IC₅₀ values: Met...

A potent and selective inhibitor (IC₅₀ = 700 nM) of vascular endothelial growth factor receptor 2 (VEGFR 2) (also known as Flk1). Very weak inhibitor of PDGFR-kinase (IC₅₀ >50 µM), EGFR-kinase (IC₅₀...

SU 16f is a potent, cell-permeable and selective platelet-derived growth factor receptor β (PDGFRβ) inhibitor (IC₅₀ = 10 nM). It displays > 14-fold, > 229-fold and > 10000-fold selectivity over...

SU 3327 is a selective inhibitor of c-Jun N-terminal kinase (JNK). It shows an IC₅₀ of 0.7 μM in the kinase assay. It Inhibits the protein-protein interaction between JNK and JIP with an IC₅₀ of 239...

Cell-permeable. A potent and ATP-competitive inhibitor of PDGF, VEGF and FGF receptor tyrosine kinases (RTKs) with IC₅₀ values of 0.06, 2.43, 3.04 and > 100 μM at PDGFRβ, VEGFR2, FGFR1 and EGFR...

SU-5214 is a modulator of tyrosine kinase signal transduction.SU-5214 is a modulator of tyrosine kinase signal transduction.B1307 | SU-5214 DataSheetAlternate Name/Synonyms:...

A potent and selective inhibitor of fibroblast growth factor receptor (FGFR) (IC₅₀ = 0.03 µM for FGFR1) and vascular endothelial growth factor receptors (VEGFR) (IC₅₀ = 0.02 µM for VEGFR2). In...

SU-5416 is a potent tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR-2; Flk-1/KDR). In addition to inhibiting VEGFR-2 (IC₅₀ = 1 μM),...

SU-5614 is a potent and selective FLT3 (FMS-like tyrosine kinase 3) inhibitor. SU5614 has inhibitory activity for FLT3 and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3...

SU-6656 is a potent and selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively). In NIH 3T3 cells, SU-6656 inhibits PDGF-/Src-driven...