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A widely used fluorogenic substrate for 20S proteasome, calpains and other chymotrypsin-like proteases. Cleavage of this AMC peptide by the enzymes generates strongly fluorescent AMC that is...

K660 | Succinate Dehydrogenase Activity Colorimetric Assay Kit DataSheet

E4595 | Succinate Dehydrogenase SDH Human Elisa Kit DataSheet

E4596 | Succinate Dehydrogenase SDH Rat Elisa Kit DataSheet

K649 | Succinate Succinic Acid Colorimetric Assay Kit DataSheet

Succinobucol is a phenolic antioxidant with anti-inflammatory and antiplatelet effects. It displays anti-platelet activity in rabbit and rat blood and reverses the increase in platelet aggregation in...

K597 | Succinyl-CoA Synthetase Activity Colorimetric Assay Kit DataSheet

Sucralfate is a basic aluminum sucrose sulfate complex that displays gastroprotective activity. It inhibits rat pepsin in a concentration-dependent manner and pepsin activity in isolated human...

Sucrose Colorimetric/Fluorometric Assay Kit | K626

Sulfamethoxazole is an antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Inhibits folic acid synthesis in prokaryotesSulfamethoxazole is an...

An anti-inflammatory agent and GST inhibitor. Sulfasalazine inhibits TNF-α and LPS-induced NF-κB activation in SW620 colon cancer cells. It also inhibits degradation of IκBα and prevents nuclear...

K675 | Sulfatase Activity Assay Kit Colorimetric DataSheet

K415 | Sulfate Assay Kit DataSheet

Sulfatinib is a potent, orally bioavailable and highly selective tyrosine kinase inhibitor against VEGFR1/2/3, FGFR1 and CSF1R with IC₅₀s of in a range of 1 to 24 nM.Sulfatinib is a potent, orally...

KEY FEATURES: • Sulfo-LC-SPDP releases a byproduct, pyridine-2-thione after reacting with free sulfhydryl groups. By measuring the release of this byproduct at 343 nm, the reaction can be easily...

KEY FEATURES: • Sulfo-NHS assists in stabilizing the protein-EDC intermediate, thus allowing for a more efficient crosslinking reaction. • Water-soluble; can be used under physiologic conditions •...

KEY FEATURES: • Sulfo-NHS-Biotin is amine-reactive and has a spacer arm length of 13.5 Å. • Water-soluble; can be used under physiologic conditions • The amide bond formed is permanent and the...

KEY FEATURES: • Amine-reactive; has a spacer with arm length of 22.4 Å which helps to minimize steric hindrance to biotin labeling • More water-soluble than the corresponding NHS compound without...

KEY FEATURES: • Sulfo-NHS-SS-Biotin is amine-reactive and • Has a long chain spacer arm (24.3 Å) separating the biotin group from the amino-reactive sulfo-NHS ester • Water-soluble; can be used...

KEY FEATURES & APPLICATIONS: • It contains an NHS ester that reacts with primary amines and a nitrophenylazide group that is photoreactive at 320-350 nm • Non-cleavable and irreversible •...

KEY FEATURES: • Amine reactive Sulfo-NHS ester that crosslinks efficiently with primary amine-containing molecules • Has a maleimide functional group that can be utilized to react specifically with...

A zwitterionic detergent useful for solubilization of membrane proteins. Retains its zwitterionic character over a broad pH range.Sulfobetaine 3-16 is a zwitterionic detergent useful for...

K4207 | Sulfonamides residue Elisa Kit DataSheet

Sulforaphane is an isothiocyanate found in cruciferous vegetables such as broccoli. It has anti-cancer activity and targets multiple pathways in cancer development. It induces chemopreventative...

K943 | Sulforhodamine B Cell Cytotoxicity Assay Kit Colorimetric DataSheet

Sulindac | B3382Description: Sulindac is non-steroidal anti-inflammatory drug (NSAID) and an analgesic that has antiproliferative and apoptotic effects. It inhibits the expression and activity of...

SUMO (Small Ubiquitin-like MOdifiers) fusion tag (Smt3), as an N-terminal fusion partner, has been shown to enhance functional protein production in prokaryotic and eukaryotic expression systems with...

SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation and transcriptional regulation. SUMO1 functions in a manner similar to ubiquitin in that it is...

SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation and transcriptional regulation. SUMO1 functions in a manner similar to ubiquitin in that it is...

SUMO modification has been implicated in functions such as nuclear transport, chromosome segregation and transcriptional regulation. SUMO functions in a manner similar to ubiquitin in that it is...

Sunitinib is a potent inhibitor of CSF-1 receptor kinase in an enzyme assay, with an IC₅₀ of 7 nM, and inhibits receptor phosphorylation in a cellular assay with an IC₅₀ of 61 nM. Sunitinib inhibits...

Sunitinib is a free base form of Sunitinib malate (Cat. No. 1611).Sunitinib is a free base form of Sunitinib malate (Cat. No. 1611).2097 | Sunitinib, Free base DataSheetAlternate Name/Synonyms:...

K824 | SuperBrite ECL Western Blot Substrate/Detection Kit DataSheet

K4005 | SuperBrite Elisa HRP Chemiluminescence Substrate Kit DataSheet

Immunohistomounting medium (IHM) is a permanent aqueous mounting medium designed for permanent mounting of tissue sections and cell smears with peroxidase and alkaline phosphatase chromogens that...

The SuperMount™ Mounting Medium was prepared using a unique, stable formula to preserving fluorescence of fluorescein, rhodamine, Texas Red, Cy3, Cy5, as well as other fluorescent reagents. Sections...

Superoxide Dismutase (SOD) is an oxidoreductase that catalyzes the reaction between superoxide anions and hydrogen to yield molecular oxygen and hydrogen peroxide. The enzyme protects the cell...

3458BP | Superoxide Dismutase (SOD-1) Blocking Peptide DataSheetAntibody Target: SOD-1Accession #: AAR21563Gene ID: 6647Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5...

6168 | Superoxide Dismutase 1 (SOD-1) Antibody (72B1) DataSheet

6641 | Superoxide Dismutase 1 (SOD-1) Antibody DataSheet

E4582 | Superoxide Dismutase 1 SOD1 Human Elisa Kit DataSheet

E4583 | Superoxide Dismutase 1 SOD1 Mouse Elisa Kit DataSheet

E4584 | Superoxide Dismutase 1 SOD1 Rat Elisa Kit DataSheet

SOD2 is part of the iron/manganese superoxide dismutase family. It encodes a mitochondrial protein that forms a homotetramer and binds one manganese ion per subunit. SOD2 binds to the superoxide...

6169 | Superoxide Dismutase 2 (SOD-2) Antibody (2A1) DataSheet

6170 | Superoxide Dismutase 3 (SOD-3) Antibody (1H12) DataSheet

6171 | Superoxide Dismutase 4 (SOD-4) Antibody (3A1) DataSheet

Superoxide dismutase, Mn, also known as sodA, is a member of the iron/manganese superoxide dismutase family. SodA destroys radicals which are normally produced within the cells and which are toxic...

K335 | Superoxide Dismutase SOD Activity Colorimetric Assay Kit DataSheet

3458 | Superoxide Dismutase (SOD-1) Antibody DataSheet

Suplatast tosylate is a Th2 cytokine inhibitor and an immunomodulator. It suppresses eosinophil infiltration, IgE production, and allergic inflammation by suppressing the production of IL-4 and IL-5 ...

A P2x and P2y purinergic receptor antagonist that displays antitumor, antiangiogenic and antiparasitic activities. Inhibits sirtuin 1, sirtuin 5 and topoisomerase II. Inhibits the cell surface...

3160 | Survivin Antibody DataSheet

3160BP | Survivin Blocking Peptide DataSheetAntibody Target: SurvivinAccession #: O15392Gene ID: 332Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

E4502 | Survivin Human Elisa Kit DataSheet

Survivin, a member of the inhibitor of apoptosis (IAP) family, is also called baculoviral inhibitor of apoptosis repeat-containing 5 or BIRC5 and in humans is encoded by the BIRC5 gene. The survivin...

5010 | Sushi Antibody DataSheet

’s Sushi Peptide S3 is a trimer of one of the high endotoxin-binding domains, Sushi 3 (or S3) within Factor C, a lipopolysaccharide (LPS)-sensitive serine protease of the horseshoe crab (Limulus...

6832 | Suz12 polyclonal antibody DataSheet

SW-033291 is a potent inhibitor of 15-hydroxy prostaglandin dehydrogenase (15-PGDH) (Ki = ~0.1 nM). It rapidly increases the levels of PGE2 in bone marrow and other tissues in mice after...

SW-044248 is a selective Topoisomerase I inhibitor. It is extremely potent and selectively toxic to NSCLC killing ~15% of a 74 NSCLC cell lines. It was not toxic to immortalized human bronchial cell...

6285 | Swi6 Antibody DataSheet

6285BP | Swi6 Blocking Peptide DataSheetAntibody Target: Swi6 Accession #: Q1ZZU3Gene ID: 375757Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

SYBR Green I is a highly sensitive fluorescent DNA binding stain for staining of double stranded DNA (dsDNA) or oligonucleotides in agarose or polyacrylamide gels.SYBR Green I is a highly sensitive...

Syk Inhibitor II is an ATP-competitive inhibitor of spleen tyrosine kinase (Syk) with an IC₅₀ of 41 nM. It is much less potent against PKCε, PKCβII, ZAP-70, Btk, and Itk. It prevents FcεRI-mediated...

Cell-permeable. An oxindole derivative that acts as a potent, reversible, and ATP-competitive Spleen tyrosine kinase (Syk) inhibitor (IC₅₀ = 14 nM). Has been shown to effectively inhibit...

R406 is a potent SYK (Spleen Tyrosine Kinase) inhibitor (IC₅₀ = 41 nM). R406 strongly inhibits SYK but not Lyn, and displays 5-fold less potency towards FLT3. R406 induces apoptosis in diffuse large...

6008 | Synapsin Antibody DataSheet

6008BP | Synapsin Blocking Peptide DataSheetAntibody Target: Synapsin Accession #: P17600Gene ID: 6853Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) Synapsin...

3177 | Synaptotagmin Antibody DataSheet

3177BP | Synaptotagmin Blocking Peptide DataSheetAntibody Target: SynaptotagminAccession #: P21707Gene ID: 25716Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

3643R | Syndecan-1 Antibody DataSheet

3643RBP | Syndecan-1 Blocking Peptide DataSheetAntibody Target: Syndecan-1 Accession #: P18827 Gene ID: 6382Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

E4354 | Syndecan-1 SDC1 Human Elisa Kit DataSheet

3824 | Syndecan-3 Antibody DataSheet

3824BP | Syndecan-3 Blocking Peptide DataSheetAntibody Target: Syndecan-3 Accession #: O75056Gene ID: 9672Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) Syndecan-3...

3644 | Syndecan-4 Antibody DataSheet

3644BP | Syndecan-4 Blocking Peptide DataSheetAntibody Target: Syndecan-4Accession #: P31431Gene ID: 6385Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Syrosingopine is an inhibitor of the vesicular monoamine transporters. Recently, it has been shown that the anticancer activity of the widely used diabetic drug metformin is strongly potentiated by...

SZL P1-41 is a specific Skp2 inhibitor that binds to the F-box domain of Skp2 to prevent Skp1 association and Skp2 SCF complex formation. Also inhibits Skp2-mediated p27 and Akt ubiquitination in...

T-5224 is a selective inhibitor of c-Fos/activator protein (AP)-1 that ameliorates liver injury and improves survival through decreasing production of pro-inflammatory cytokines and chemokines in...

T-705 (Favipiravir) is an antiviral drug that selectively inhibits the RNA-dependent RNA polymerase of influenza virus. It is phosphoribosylated by cellular enzymes to its active form,...

T0070907 is a potent and selective antagonist of the human PPARγ (IC50 = 1 nM). T0070907 suppresses breast cancer cell proliferation and motility via both PPARγ-dependent and –independent mechanisms...

T0901317 is a potent and selective agonist for both LXR (liver X receptor) and FXRs (bile acid farnesoid X receptors), with EC50 of ~50 nM and 5 μM, respectively, inhibits nuclear factor/κB (NF/κB)...

T4 DNA ligase catalyzes the formation of phosphodiester bonds between 5’-phosphate and 3’-hydroxy ends of double-stranded DNA. Single stranded nicks in double-stranded DNA are also closed by T4 DNA...

T4 DNA Ligase Reaction Buffer (2X) consists of 132 mM Tris-HCl (pH 7.6), 15% PEG 6000, 20 mM MgCl2, 2 mM DTT, and 2 mM ATP.9102 | T4 DNA Ligase Buffer DataSheetSort Name: T4 DNA Ligase BufferLabel...

T4 DNA Ligase catalyzes the formation of a phosphodiester bond between juxtaposed 5' phosphate and 3' hydroxyl termini in duplex DNA or RNA. This enzyme joins blunt-end and cohesive-end termini as...

T4 DNA Polymerase catalyzes the 5’→3’ synthesis of DNA from a single stranded, primed DNA templateM1211 | T4 DNA Polymerase DataSheetSort Name: T4 DNA PolymeraseLabel Name: T4 DNA PolymeraseTaglines:...

T4 Gene 32 Protein is a single-stranded DNA (ssDNA) binding protein which is required for T4 bacteriophage replication, recombination and repair.M1232 | T4 Gene 32 Protein DataSheetSort Name: T4 Gene...

T4 Polynucleotide Kinase catalyzes the transfer of the γ-phosphate from ATP to the 5´-hydroxyl terminus of double and single-stranded RNA and DNA, oligonucleotides or nucleoside...

T4 RNA Ligase 1 (ssRNA Ligase) catalyzes the ATP-dependent formation of a 3’→5’ phosphodiester bond by ligating the 5’ phosphoryl-terminated nucleic acid donor to a 3’ hydroxyl-terminated nucleic...

T4 RNA Ligase 2 (dsRNA Ligase) catalyzes the ATP-dependent formation of a 3’→5’ phosphodiester bond catalyzing intramolecular and intermolecular RNA strand joining. Unlike T4 RNA Ligase 1 (M1218-100)...

T4 RNA Ligase 2 (Truncated) catalyzes the formation of a phosphodiester bond between a pre-adenylated 5’ phosphate (DNA or RNA) and the 3’ hydroxyl of RNA. This truncated enzyme contains the first...

T5601640, also known as T56-LIMKi, has high specific inhibitory activity for LIMK2 and shows little or no activity with LIMK1. It decreases levels of phosphorylated coflin (p-coflin) inhibiting...

T7 Endonuclease I recognize and cleaves mismatched DNA, heteroduplex DNA, cruciform DNA, Holliday structures and/or junctions, as well as nicked double-stranded DNAM1221 | T7 Endonuclease I...

3987 | T7 Epitope -Tag Antibody DataSheet

TA-01 is a potential inhibitor of Casein kinase ε(CK1ε), casein kinase 1δ (CK1δ) and mitogen activated protein kinase(MAPK) p38α with IC₅₀ of 6.4, 6.8 and 6.7 nM, respectively. It shows complete...

TA-02 is a potent inhibitor of p38 MAPK (IC₅₀ = 20 nM). It induces differentiation in cardiomyocytes from human embryonic stem cells after mesoderm induction.TA-02 is a potent inhibitor of p38 MAPK...

3682 | TAB1 Antibody DataSheet

TACE (TNF-alpha converting enzyme, ADAM17) is a membrane-bound Metalloprotease from the ADAM (a disintegrin and Metalloprotease) family of proteins. It cleaves 26kDa type II membrane-bound precursor...