26

6674 | TDRD4 Antibody DataSheet

TDZD-8 is a non-ATP competitive inhibitor of the serine/threonine kinase glycogen synthase kinase 3β (GSK3β; IC₅₀ = 2 µM), binding to the active site of GSK3β. It does not significantly affect the...

TECK is a CC chemokine, specifically expressed by thymic stromal cells, and signals through the CCR9 receptor. TECK is chemotactic towards activated macrophages, thymocytes and dendritic cells...

Tectorigenin (TEC) is an isoflavone isolated from various medicinal plants. It has been reported to display a variety of biological activities including antitumor and antibacterial effects, free...

TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 μM for TEAD4⋅Yap1 protein-protein interaction. TED-347 specifically...

Tedizolid | B3389Description: Tedizolid is an oxazolidinone-class antibiotic. It exerts its bacteriostatic microbial activity through inhibition of protein synthesis by binding to the 50S ribosomal...

Teicoplanin is a lipoglycopeptide antibiotic extracted from Actinoplanes teichomiceticus. Acts against Gram-postive bacteria including methicillin-resistant Staphylococcus aureus and Enterococcus...

Telaprevir is a peptidomimetic inhibitor of hepatitis C virus protease. Telaprevir inhibits the hepatitis C virus NS3-4A serine protease, blocking the viral polyprotein processing. The dose dependent...

Telatinib (Bay 57-9352) is a potent small molecule inhibitor of VEGFR2, VEGFR3, PDGFα, and c-Kit with IC₅₀s of 6, 4, 15 and 1 nM, respectively.Telatinib (Bay 57-9352) is a potent small molecule...

Telithromycin is a semi-synthetic erythromycin derivative that belongs to a class of ketolide antibiotics. Similar to the macrolide antibiotics, telithromycin prevents bacterial growth by interfering...

Telotristat | B3386Description: Telotristat is an oral, small molecule inhibitor of tryptophan hydroxylase 1 (TPH1) IC50 = 16 nM) that is used in the treatment of symptoms of carcinoid syndrome...

3668 | TEM-8/ATR1 Antibody DataSheet

3668BP | TEM-8/ATR1 Blocking Peptide DataSheetAntibody Target: TEM-8/ATR1 Accession #: AAL11999Gene ID: 69538Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

A DNA methylating agent. A second-generation imidazotetrazine prodrug that undergoes spontaneous conversion under physiological conditions to the active alkylating agent MTIC...

TEMPOL is a piperidine nitroxide and spin label with superoxide dismutase (SOD) mimetic activity. It is a membrane permeable, free radical scavenger. It inhibits lipid peroxidation induced by iron...

mTOR inhibitor with anti-cancer activity. It has anti-angiogenic effects which may contribute to the antitumor activity of temsirolimus observed in breast cancer. Temsirolimus shows synergistic in...

Tenalisib is a potent, and selective PI3Kδ and PI3Kγ inhibitor with IC₅₀ values of 25 and 33 nM, respectively. Displays good selectivity over p110α (>300-fold) and p110β (>100-fold) isoforms...

3628BP | Tenascin (TN-C) Blocking Peptide DataSheetAntibody Target: Tenascin (TN-C) Accession #: P24821Gene ID: 3371Appearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.5 mg/ml)...

3628 | Tenascin (TN-C) Antibody DataSheet

Teneligliptin is a potent DPP-4 (dipeptidylpeptidase-4) inhibitor, that competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC₅₀s of approximately 1 nM. Useful...

Teniposide is a podophyllotoxin derivative that acts as a topoisomerase II inhibitor. Its cytostatic effects are related to its ability to stabilize the DNA-topoisomerase II complex during DNA...

A water-soluble diester prodrug of the active ingredient Tenofovir, that belongs to a class of antiretroviral drugs known as nucleotide analogue reverse transcriptase inhibitors (NtRTIs), which block...

Tenovin-1 is a small molecule p53 activator that protects against MDM2-mediated p53 degradation. It acts through inhibition of the protein-deacetylating activities of SirT1 and SirT2. Elevates levels...

Tenovin-3 is a p53 activator and an inhibitor of SIRT2.Tenovin-3 is a p53 activator and an inhibitor of SIRT2.B1828 | Tenovin-3 DataSheetAlternate Name/Synonyms:...

Tenovin-6 is a SirT2 inhibitor and a p53 activator. It is a water-soluble analog of Tenovin-1. Tenovins inhibit the protein-deacetylase activities of SirT1 and SirT2. The IC₅₀ for inhibiting human...

TEPP-46 (ML-265) is a potent and selective PKM2 activator. TEPP-46 activates tumor-specific PKM2 (EC₅₀ = 92 nM) by binding to the dimer-dimer interface between two subunits of PKM2 and inducing...

Terbinafine is an allylamine antifungal agent that acts as a squalene epoxidase inhibitor.Terbinafine is an allylamine antifungal agent that acts as a squalene epoxidase inhibitor.B2423 | Terbinafine...

Terbinafine hydrochloride is a selective TASK3 (TWIK-related acid-sensitive K⁺ channel 3, KCNK9, K2P9.1) activator (pEC₅₀ = 6.2). It displays >10-fold selectivity for TASK3 over TREK2, TRESK, THIK1...

Tergitol™ 15-S-9 is a linear non-ionic surfactant containing a secondary ethoxylated alcohol. Useful for solubilization of integral membrane proteins such as phosphatidylinositol kinase.Tergitol™...

’s Terrific Broth is used with glycerol in cultivating recombinant strains of E. coli. Terrific broth is a highly enriched medium for improving yield in plasmid bearing E. coli. Recombinant strains...

Terminal transferase (TdT) is a template independent polymerase that catalyzes the addition of deoxynucleotides to the 3' hydroxyl terminus of DNA molecules.M1249 | Terminal Transferase (20,000 U/ml)...

Isolated from Albophoma yamanashiensis. An acyl-CoA:cholesterol acyltransferase (ACAT) isozymes ACAT1 and ACAT2 inhibitor. Also acts as a tremorgen and cholesteryl ester (CE) synthesis inhibitor...

6793 | TERT Antibody DataSheet

K4187 | TERT Human Elisa Kit DataSheet

K7417 | Testosterone human Elisa Kit DataSheet

K7418 | Testosterone mouse/rat Elisa Kit DataSheet

TestStrip™ Ammonia lab strips are semi-quantitative strips that are strips that measures ammonia (NH3/NH4+) dissolved in water (0-100 ppm).M1091 | TestStrip™ Ammonia DataSheetSort Name: TestStrip™...

TestStrip™ Glucose lab strips are semi-quantitative strips that measures glucose concentration in mg/dL and are specific to glucose (0.1 – 0.01%).M1093 | TestStrip™ Glucose DataSheetSort Name:...

TestStrip™ Phosphate lab strips are strips that measure phosphate ions (PO4) in water (0-100 ppm).M1092 | TestStrip™ Phosphate DataSheetSort Name: TestStrip™ PhosphateLabel Name: TestStrip™...

Tetracycline is a broad-spectrum antibiotic that prevents bacterial growth by inhibiting protein synthesis. It binds to a single site in the 30S ribosomal subunit which prevents attachment of...

E4273 | Tetracyclines Elisa Kit DataSheet

Tetrahydrocurcumin (THC) is a major metabolite of curcumin that displays antioxidant and anti-inflammatory properties. It has been shown to have protective effects against diabetes and vascular...

Tetrahydropiperine is a derivative of piperine (Cat. No. B2086) that displays various biological activities. It acts as an agonist of transient receptor potential vanilloid type 1 (TRPV1; EC50 = 6.3...

A competitive cytidine deaminase inhibitor and multidrug resistance modulator. Makes tumor cells more sensitive to radiation therapy making it useful for cancer treatmentTetrahydrouridine is a...

Tetrahydroxanthohumol (TXN) is a synthetic derivative of the flavonoid antioxidant Xanthohumol (Cat. No. 2258). TXN attenuates high-fat diet-induced hepatic steatosis by antagonizing PPARγ. A...

Tetrandrine is a bisbenylisoquinoline alkaloid that displays very broad pharmacological actions, including anti-tumor activity. It enhances the cytotoxicity of MDR-related drugs via modulation of...

K842 | TEV Protease Activity Assay Kit Fluorometric DataSheet

6689 | TEV Protease Antibody DataSheet

K843 | TEV Protease Inhibitor Screening Kit Fluorometric DataSheet

3885 | TFAM Antibody DataSheet

3885BP | TFAM Blocking Peptide DataSheetAntibody Target: TFAMAccession #: Q91ZW1Gene ID: 83474Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to...

5745 | TFF-2/Spasmolysin Antibody DataSheet

Proteins of the TFF family are characterized by having at least 1 copy of the trefoil motif, a 40-amino acid domain that contains 3 conserved disulfides. Trefoil Factors are stable secretory proteins...

5893 | TFF1 Antibody DataSheet

The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. Recombinant human TFF1 is...

3721 | TFP1/HADHA Antibody DataSheet

3721BP | TFP1/HADHA Blocking Peptide DataSheetAntibody Target: TFP1 Accession #: P40939Gene ID: 3030Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3379 | TFPI Antibody DataSheet

3379BP | TFPI Blocking Peptide DataSheetAntibody Target: TFPIAccession #: P10646Gene ID: 7035Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate buffered...

K4185 | TFR Human Elisa Kit DataSheet

TG101209 is a potent and selective inhibitor of Janus Kinase 2 (JAK2) (IC50 = 6 nM). It displays 28-fold selectivity over JAK3 (IC50 = 169 nM). TG101209 induces dose- and time-dependent cytotoxicity...

Cell-permeable. A potent, specific, reversible, and ATP-competitive inhibitor of Cdc2-like kinase (Clk) (Ki = 10 nM for mClk1/Sty; IC₅₀ = 20 nM, 200 nM, >10 µM, and 15 nM for mClk1, mClk2, mClk3, and...

TG100-115 is a PI3K γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively).TG100-115 is a PI3K γ and -δ inhibitor (IC50 = 83 and 235 nM, respectively).B1667 | TG100-115 DataSheetAlternate...

TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ.TG100713 is a pan-PI3K inhibitor against PI3Kγ, PI3Kδ, PI3Kα and PI3Kβ.B1717 | TG100713 DataSheetAlternate Name/Synonyms:...

TG101348 is a potent, and selective inhibitor of JAK2 (IC₅₀ = 3 nM). It has a 35- and 334-fold selectivity over JAK3 and JAK1, respectively.TG101348 is a potent, and selective inhibitor of JAK2 (IC₅₀...

TG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2. Displays low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4,...

E4508 | TGF beta-1 Human Elisa Kit DataSheet

E4509 | TGF beta-1 Mouse Elisa Kit DataSheet

E4510 | TGF beta-1 Rat Elisa Kit DataSheet

Transforming growth factor-betas (TGF-s) mediate many cell-cell interactions that occur during embryonic development. Three TGFs have been identified in mammals. TGF-Beta 1, TGF-Beta 2 and TGF-Beta 3...

The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggests that individual TGF- isoforms (TGF-1, -2 and...

5559 | Anti-TGF-?1 Polyclonal Antibody DataSheet

5339 | TGF-alpha Antibody DataSheet

K4339 | TGF-alpha human Elisa Kit DataSheet

Transforming Growth Factor- (TGF-) stimulates the proliferation of a wide range of epidermal and epithelial cells. TGF- has been shown to play a role in the autocrine growth of certain transformed...

5559BP | TGF-b1 Blocking Peptide DataSheetAntibody Target: TGF-β1 Accession #: P01137 Gene ID: 7040Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: In phosphate-buffered saline (PBS)...

5344 | TGF-b3 Polyclonal Antibody DataSheet

5636R | TGF-beta Receptor I Antibody DataSheet

5636RBP | TGF-beta Receptor I Blocking Peptide DataSheetAntibody Target: TGF-beta Receptor I Accession #: EDL78209.1Gene ID: 29591Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50...

5639R | TGF-beta Receptor II Antibody DataSheet

5639RBP | TGF-beta Receptor II Blocking Peptide DataSheetAntibody Target: TGF-b Receptor IIAccession #: NP_112394Gene ID: 81810Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg...

5642 | TGF-beta Receptor III Antibody DataSheet

K4342 | TGF-beta1 human Elisa Kit DataSheet

K4343 | TGF-beta1 mouse Elisa Kit DataSheet

K4344 | TGF-beta1 rat Elisa Kit DataSheet

TGF-1 (Transforming Growth Factor-1) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed...

5340 | TGF-beta2 Antibody DataSheet

5343RBP | TGF-beta2 Blocking Peptide DataSheetAntibody Target: TGF-beta2 Accession #: BAG35929Gene ID: 7042Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

TGF-2 (Transforming Growth Factor-2) is a member of the superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed...

5344R | TGF-beta3 Antibody DataSheet

5344RBP | TGF-beta3 Blocking Peptide DataSheetAntibody Target: TGF-beta3 Accession #: CAA33024Gene ID: 7043Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in...

Transforming growth factor 3 (TGF-3) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed...

TGN-020 is an inhibitor of aquaporin 4 (AQP4), the most abundant water channel in brain. It inhibits AQP4 inhibitor with an IC₅₀ of 3 μM in vitro. Pretreatment with the AQP4 inhibitor TGN-020...

TGR-1202 (also known as RP5264), is a highly specific inhibitor of PI3Kδ, targeting the δ isoform with nanomolar potency and several-fold selectivity over the α, β, and g isoforms of PI3K.TGR-1202...

Cell-permeable, small molecule agonist of TGR5 G-protein coupled receptor. This agonist has shown to increase glucagon like peptide-1 (GLP-1) secretion from primary intestinal cells.TGR5 Receptor...

TGR5 Receptor Agonist, a potent TGR5(GPCR19) agonist, showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).TGR5 Receptor Agonist, a potent TGR5(GPCR19)...

Cell-permeable. A potent and selective inhibitor of PI 3-K isoforms p110β/p110δ(IC₅₀ p110β = 0.13 µM, p110δ = 0.63 µM).TGX-115 is a potent and selective inhibitor of PI 3-K isoforms p110β/p110δ(IC₅₀...

TGX-155 is an inhibitor of phosphoinositide 3-kinase (PI3K). PI3Ks and their lipid product phosphatidylinositol-3,4,5-trisphosphate are involved in signaling events in many cellular processes...

Cell-permeable. A potent, selective and ATP-competitive inhibitor of PI 3-kinase β (IC₅₀ = 5 nM for p110β). Inhibits other PI3K isoforms at higher concentrations (IC₅₀ = 0.1 µM for p110δ, 5 µM for...