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TH-34 is a HDAC inhibitor that displays selectivity for HDACs 6, 8 and 10 over HDACs 1, 2 and 3. TH34 induces DNA damage-mediated cell death in human high-grade neuroblastoma cell lines.TH-34 is a...

Potent, cell permeable IP3-independent intracellular calcium releaser; Inhibits microsomal Ca2+-ATPase; Stimulates arachidonic acid metabolism in macrophages.Thapsigargin is a potent, cell permeable...

Theliatinib is a potent epidermal growth factor receptor EGFR tyrosine kinase inhibitor with a Ki value of 0.05 nM and IC₅₀ of 3 nM. It exhibits strong antitumor activity in patient-derived estrogen...

Thermostable RNAse H | M1224

A fungicide and a parasiticide. Inhibits angiogenesis in both human cells in vitro and in Xenopus embryos in vivo at a concentration of 100-250 µM. Also acts as a vascular disrupting agent (VDA)...

Thiamet G is a potent and selective inhibitor of O-GlcNAcase with a Ki value of 21 nM. It increases cellular O-GlcNAc-modified protein levels with an EC₅₀ of 30 nM and blocks phosphorylation of tau...

Cell-permeable. Helps in promoting human embryonic stem cell (hESC) survival by > 30-fold. Thiazovivin enhances the efficiency of fibroblast reprogramming to generate induced pluripotent stem cells...

An analog of NAD. Use of Thio-NAD instead of NAD (Cat. No. 2734) as a substrate for NAD(+)-consuming enzymes is more advantageous since the reduced form of Thio-NAD exhibits a substantial increase in...

An antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor and axonal cytoskeleton modulator; apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I...

Ready-to-use fluorogenic substrate for Trx. Trx activity can be quantified by fluorescent detection of oxidized Glutathione after reduction of the disulfide bond at 490/525 nm, using a fluorometer or...

6166 | Thioredoxin 1 Antibody (3A1) DataSheet

6167 | Thioredoxin 2 Antibody (4C5) DataSheet

Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling...

6164 | Thioredoxin Reductase 1 Antibody (19A1) DataSheet

7005 | Thioredoxin Reductase 1 (TXNRD1) Antibody DataSheet

6165 | Thioredoxin Reductase 2 Antibody (7B2) DataSheet

K763 | Thioredoxin Reductase Activity Colorimetric Assay Kit DataSheet

Thioridazine is a dopamine receptor antagonist that displays antipsychotic activity. It suppresses several types of cancer and has specificity for leukemia stem cells. Also displays potent antitumor...

Thiostrepton is a large cyclic antibiotic commonly used in topical antibiotic ointments. It inhibits bacterial protein synthesis. It blocks translation by interfering with elongation factors (EF)...

THPP is a versatile, water-soluble and air-stable reducing agent, useful for the rapid, irreversible reductive cleavage of disulfide bonds in both aqueous and buffered aqueous-organic media. THPP...

Threonine dehydrogenase (EC 1.1.1.103) is a -NAD+ coenzyme dependent enzyme, from the group of short chain alcohol dehydrogenases. It is a key enzyme in L threonine catabolism in microorganisms and...

K373 | Thrombin Activity Fluorometric Assay Kit DataSheet

6685 | Thrombin Antibody DataSheet

K377 | Thrombin Cleavage Kit DataSheet

E4522 | Thrombin Human Elisa Kit DataSheet

K374 | Thrombin Inhibitor Screening Kit Fluorometric DataSheet

Thrombin Sepharose beads are designed for efficient cleavage of recombinant fusion proteins, containing a thrombin cleavage site (e.g. Leu-Val-Pro-Arg-ll-Gly-Ser; ll: cleavage site), circumventing...

Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein...

Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein...

Thrombin enzyme (Activated Factor IIa) is an important clotting promoter that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a coagulation protein...

Thrombospondin (TSP) is a cellular adhesion protein isolated from human platelets that had been stimulated with thrombin . TSP is a component of the coagulation mechanism and is believed to have...

Thrombospondin-1 is believed to play a role in cell migration and proliferation, during embryogenesis and wound repair. Also, it has been used as a potential regulator of tumor growth and metastasis...

3700 | Thromboxane B2 Antibody DataSheet

3700BP | Thromboxane B2 Blocking Peptide DataSheetAntibody Target: Thromboxane B2 Accession #: N/AGene ID: N/AAppearance: Colorless liquidConcentration: 0.2 mg/mlFormulation: 50 µg (0.2 mg/ml) in...

6778 | Thy1/CD90 Antibody (NT) DataSheet

E4291 | Thymidine kinase 1 cytosolic Human Elisa Kit DataSheet

E4292 | Thymidine kinase 1 cytosolic Rat Elisa Kit DataSheet

E4293 | Thymidine kinase 2 mitochondrial Human Elisa Kit DataSheet

Thymoquinone is a natural phytochemical that displays anti-inflammatory properties, blocking the synthesis of leukotrienes. It inhibits the growth of leukemia cells (IC₅₀= 1.5 μg/ml), inducing...

Thymosin 1 is a peptide fragment derived from prothymosin alpha, a protein that in humans is encoded by the PTMA gene. Thymosin 1 is believed to be a major component of Thymosin Fraction 5...

Thymosin-4 is a small, actin-sequestering protein belonging to the thymosin- family that is found at high concentrations within the spleen, thymus, and peritoneal macrophages, where it is most...

K5351 | Thyroid Peroxidase [TPO] IgG human Elisa Kit DataSheet

K7411 | Thyroid Stimulating Hormone human Elisa Kit DataSheet

The thyroxine binding globulin (TBG, also known as Serpin A7) is a protein responsible for carrying the thyroid hormones thyroxine and 3,5,3'-triiodothyronine in the bloodstream. Mutations in TBG...

K7413 | Thyroxine T4 human Elisa Kit DataSheet

K7421 | Thyroxine T4 Mouse/Rat Elisa Kit DataSheet

THZ1 is a potent, cell-permeable, and selective covalent CDK7 inhibitor (IC₅₀ = 3.2 nM) that preferentially diminishes transcription in cancer cells. It displays unprecedented ability to target a...

THZ1 is a potent, cell-permeable, and selective covalent CDK7 inhibitor (IC₅₀ = 3.2 nM) that preferentially diminishes transcription in cancer cells. It displays unprecedented ability to target a...

Tiagabine is a selective inhibitor of GABA transporter 1 (GAT-1) and a GABA uptake inhibitor. It shows an IC₅₀ of 49 nM for GAT-1 expressed in CHO cells. It reduces allodynia in a rodent model of...

Ticarcillin is a β-lactam antibiotic with a broad spectrum of bactericidal activity against many gram-positive and gram-negative aerobic and anaerobic bacteria. It is commonly used in combination...

Potent mechanism-based inhibitor of CYP2C19, Anti-platelet drugPotent mechanism-based inhibitor of CYP2C19, Anti-platelet drug2919 | Ticlopidine hydrochloride DataSheetAlternate Name/Synonyms:...

Tideglusib is a potent, irreversible, non ATP-competitive glycogen synthase kinase-3 (GSK-3) inhibitor (IC₅₀ = 60 nM).Tideglusib is a potent, irreversible, non ATP-competitive glycogen synthase...

Tie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 ΜmTie2 kinase inhibitor is a potent and selective Tie2 inhibitor with IC50 of 0.25 mΜB1338 | Tie2 Kinase Inhibitor...

3774 | TIF1a/TRIM24 Antibody DataSheet

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of...

TIGAR is a p53-inducible enzyme that catalyzes the hydrolysis of fructose-2-6 bisphosphate (F-2-6-BP) to fructose-6-phosphate and inorganic phosphate. F-2-6-BP is a powerful activator of...

A glycylglycine type of antibiotic derived from tetracycline. Inhibits protein translation in bacteria by binding to the 30S ribosomal subunit and blocking entry of amino-acyl tRNA molecules into the...

E4549 | TIGIT Human Elisa Kit DataSheet

Tildipirosin is a 16-membered macrolide antibiotic used in veterinary medicine. It inhibits protein synthesis in bacteria and blocks the production of biofilms. Tildipirosin is particularly effective...

A naturally occurring flavonoid that shows anti-complement, anti-inflammatory and free radical scavenger activity. Inhibits the production of the inflammatory mediators nitric oxide (NO), TNF-α and...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

Probable receptor for SEMA4A involved in the regulation of T-cell function. The interaction with SEMA4A enhances T-cell activation.P1356 | Tim-2 Mouse Recombinant DataSheetBiomolecule/Target:...

3808 | Tim-3 Antibody DataSheet

3808BP | Tim-3 Blocking Peptide DataSheetAntibody Target: Tim-3 Accession #: Q8TDQ0Gene ID: 84868Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to...

Timentin is a mixrure (15:1) of Ticarcillin Disodium Salt/Potassium Clavulanate. It acts as a β-Lactamase inhibitor. Highly effective combination against gram negative bacteria such as Agrobacterium...

TIMP-1 Mouse Elisa Kit | K4750

The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two...

The tissue inhibitor of metalloproteinases (TIMP-1) is a glycoprotein with a molecular mass of about 28-kDa. The secreted protein consists of 184 amino acids, six disuilfide bonds and two...

TIMP-2 Mouse Elisa Kit | K4752

Glycoprotein that belongs to a family which takes part in the activation and regulation of the MMP-activity. Forms a non-covalent stoichiometric complex with latent and active MMP's. Inhibits the...

TIP60 Antibody | 6125

A potent, selective, nonpeptidomimetic inhibitor of farnesyl protein transferase (FPT), an enzyme involved in protein processing (farnesylation) for signal transduction. Displays significant...

Tiplaxtinin(PAI-039) is a selective and orally efficacious inhibitor of plasminogen activator inhibitor-1 (PAI-1) with IC50 of 2.7 µM.Tiplaxtinin(PAI-039) is a selective and orally efficacious...

Tirabrutinib (ONO-4059) hydrochloride is a potent and selective BTK (Bruton’s Tyrosine Kinase) inhibitor (IC₅₀ = 2.2 nm). Tirabrutinib binds to BTK within B cells, thereby preventing B-cell receptor...

Tissue Advance Pcr Kit | M1145

K178 | Tissue Plasminogen Activator tPA Activity Assay Kit Colorimetric DataSheet

E4501 | Tissue Transglutaminase tTG Human Elisa Kit DataSheet

Tivantinib (ARQ-197) is a potent, cell-permeable inhibitor of c-Met with potential antineoplastic activity. Tivantinib binds to the c-Met protein and disrupts c-Met signal transduction pathways,...

Tivozanib (AV-951) is a potent and selective VEGFR inhibitor with IC₅₀ values of of 30, 6.5 15 nM, for VEGFR-1, VEGFR-2, and VEGFR-3, respectively. It also inhibits PDGFR and c-Kit, with lower...

TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and...

3446 | TLR1 Antibody DataSheet

3932 | TLR10 Antibody DataSheet

3932BP | TLR10 Blocking Peptide DataSheetAntibody Target: TLR10 Accession #: BAF84715Gene ID: 81793Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3931 | TLR11 Antibody DataSheet

3931BP | TLR11 Blocking Peptide DataSheetAntibody Target: TLR11 Accession #: Q6R5P0Gene ID: 239081Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3552R | TLR2 Antibody DataSheet

3552RBP | TLR2 Blocking Peptide DataSheetAntibody Target: TLR2Accession #: AAH14693Gene ID: 24088Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

A1075 | TLR2 Polyclonal Antibody DataSheet

TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. It is induced by synthetic and bacterial TLR2 agonists in human HEK-TLR2 and THP-1 cells, but only TLR2/1 signaling in murine macrophages...

3445R | TLR3 Antibody DataSheet

3445RBP | TLR3 Blocking Peptide DataSheetAntibody Target: TLR3 Accession #: EDL35548Gene ID: 142980Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3445 | TLR3 Polyclonal Antibody DataSheet

TLR4 is a member of Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and...

3253BP | TLR4 Blocking Peptide DataSheetAntibody Target: TLR4 Accession #: EDM10505.1Gene ID: 29260Appearance: Colorless liquidConcentration: 0.5 mg/mlFormulation: 50 µg (0.5 mg/ml) in phosphate...

3555R | TLR5 Antibody DataSheet