Description
4-CPPC is a potent, reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT) (IC50 = 27 µM). 4-CPPC displays17-fold selectivity for MIF-2 versus MIF-1. MIF-2 is member of the MIF cytokine superfamily.
4-CPPC is a potent, reversible and selective small molecule inhibitor of the pro-inflammatory protein macrophage migration inhibitory factor-2 (a.k.a. MIF-2 or D-DT) (IC50 = 27 µM). 4-CPPC displays17-fold selectivity for MIF-2 versus MIF-1. MIF-2 is member of the MIF cytokine superfamily.
Alternate Name/Synonyms: 4-(3-Carboxyphenyl)-2,5-pyridinedicarboxylic acid 4CPPC
Appearance: Crystalline solid
Formulation:
CAS Number: 29553-70-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₉NO₆
Molecular Weight: 287.23
Cell-Permeable?: True
Purity: ≥98% by HPLC
Solubilities:
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A pro-inflammatory protein macrophage migration inhibitory factor-2 (MIF-2) inhibitor
MDL Number:
PubChem CID: 893698
SMILES: O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
InChi: InChI=1S/C14H9NO6/c16-12(17)8-3-1-2-7(4-8)9-5-11(14(20)21)15-6-10(9)13(18)19/h1-6H,(H,16,17)(H,18,19)(H,20,21)
InChi Key: O=C(C1=NC=C(C(O)=O)C(C2=CC=CC(C(O)=O)=C2)=C1)O
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |