AGR3 Antibody (C-term) [APR06168G]

AGR3 Antibody (C-term) [APR06168G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H

Specificity: This AGR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the C-terminal region of human AGR3.

Cellular Localisation: Endoplasmic reticulum. Note=Found in the cytoplasm, which could include the endoplasmic reticulum

Molecular Weight: 19171

Clone: Polyclonal

Gene Name: AGR3

Gene ID: 155465

Function: Required for calcium-mediated regulation of ciliary beat frequency and mucociliary clearance in the airway. Might be involved in the regulation of intracellular calcium in tracheal epithelial cells.

Summary: Tissue Location: Expressed in the lung, in the ciliated cells of the airway epithelium (PubMed:25751668) . Expression increased with differentiation of airway epithelial cells (PubMed:25751668) . Not detected in the mucous cells (PubMed:25751668) . Expressed in ciliated cells in the oviduct (PubMed:26170690) . Also detected in stomach, colon, prostate and liver (PubMed:25751668) . Expressed in breast, ovary, prostate and liver cancer (PubMed:26170690) . Expression is associated with the level of differentiation of breast cancer (at protein level) (PubMed:26170690) .

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IHC-P, FC

Dilution: WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Synonyms: Anterior gradient protein 3 homolog, AG-3, AG3, hAG-3, Breast cancer membrane protein 11, AGR3, BCMP11