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Angiostatin K1-3, human recombinant | 4920
- SKU:
- 26-4920-GEN
- Availability:
- Usually shipped in 5 working days
Description
Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. A specific inhibitor of endothelial cell growth and angiogenesis. Displays increased inhibitory activity (ED =70 nM) relative to kringles 1-4 (ED = 135 nM). Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
4920 | Angiostatin K1-3 human recombinant DataSheet
Biomolecule/Target: N/A
Synonyms: Angiostatin K1-3, Angiostatin Kringles 1-3
Alternates names: Angiostatin K1-4, Angiostatin Kringles 1-4, plasminogen
Taglines: A specific inhibitor of endothelial cell growth and angiogenesis
NCBI Gene ID #:
NCBI Gene Symbol: TNFSF13B
Gene Source: Human
Accession #: D4AAC1
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 95%
Assay: SDS-PAGE
Purity: 95%
Assay #2: HPLC
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: 0.55×10 Units/mg.
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 20.7 kDa
Concentration: N/A
Appearance: Lyophilized protein
Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM Sodium Acetate, pH 5.5 and 4% mannitol.
Reconstitution Instructions: Reconstitute in sterile HO to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers or stored at 4°C for 1 week or 20°C for future use.
Amino acid sequence: N/A