Anti-ATM Antibody | A2211

The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder.

A2211 | Anti-ATM Antibody DataSheet

Antibody Target: ATM

Target Alternative Name: AT1, ATA, ATC, ATD, ATE, ATDC, TEL1, TELO1

Tag Line: Rabbit polyclonal antibody to detect ATM expression in human and mouse samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Mouse,Human

Immunogen Sequence: KLH-conjugated synthetic peptide targeting a sequence within the center region of human ATM

Accession #: Q13315

Gene ID: 472

Appearance: Colorless liquid

Form: Liquid

Concentration: 1 mg/ml

Formulation: In 0.42% Potassium phosphate; 0.87% NaCl; pH 7.3; 30% glycerol; and 0.01% sodium azide

Purification: Affinity purified

Application: Immunohistochemistry (IHC),Western Blotting

Positive Control:

Application And Usages: WB (1:500 - 1:1000), IHC (1:100 - 1:200)

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: TRUE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE