Anti-Caspase-3 (Active) Biotinylated Antibody | A2116

The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.

A2116 | Anti-Caspase-3 (Active) Biotinylated Antibody DataSheet

Antibody Target: Caspase 3

Target Alternative Name: CPP32; CPP32B; SCA-1; Active Caspase 3; CASP3; active Caspase-3; Caspase 3; Caspase-3 p12; caspase-3

Tag Line: Rabbit polyclonal antibody to detect biotinylated active Caspase 3 in human samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: Synthetic peptide mapping to the N-terminus adjacent to the cleavage site of human caspase-3

Accession #: P42574

Gene ID: 836

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: In PBS, pH 7.2, 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03% proclin

Purification: Antigen Affinity purified

Application: ELISA

Positive Control:

Application And Usages: ELISA 1:500 - 1:2000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: TRUE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE