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Anti-Diglycyl-Lysine Antibody (Clone# GX41) | A2226
- SKU:
- 26-A2226-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
Ubiquitination is one of the most important post-translational modifications that determine the functional activity and stability of the protein. It plays a significant role in multiple biological processes such as cell proliferation, differentiation, regulation of cell cycle, gene transcription, and apoptosis. Changes in the ubiquitination of proteins are linked to diseases such as cancer, inflammation, neurodegenerative, and cardiovascular diseases. Thus, it could be a potential target for drug development. Protein ubiquitination can be identified by mutational experiments and tandem mass spectrometry (MS/MS). However, a new approach relies on an antibody-based detection wherein the antibody recognizes diglycyl-lysine peptide generated as a result of the digestion of protein sample by trypsin. s Anti-Diglycyl-Lysine Antibody (Clone# GX41) can help identify the diglycyl lysine sequences that are present on the ?-amine of lysine as an adduct with no reactivity to unmodified lysine.
A2226 | Anti-Diglycyl-Lysine Antibody (Clone# GX41) DataSheet
Antibody Target: Diglycyl-Lysine
Target Alternative Name: Diglycyl-Lysine, Gly-Gly Lycine
Tag Line: Mouse monoclonal antibody to detect peptides with diglycyl modified lysine in human, rat, mouse, chicken, cow, horse, and yeast
Category: Primary antibody
Host: Mouse
Isotype: IgG
Species Reactivities: Tested in Rat. Reactivity expected in Human, Mouse, Chicken, Bovine, Equine, Yeast
Immunogen Sequence: Linear peptide corresponding to Diglycyl Lysine
Accession #:
Gene ID:
Appearance: Lyophilized powder
Form: Lyophilized
Concentration:
Formulation: In 0.2 M HEPES pH 8.5
Purification: Protein A affinity chromatography
Application: Immunoprecipitation (IP),Western Blotting
Positive Control:
Application And Usages: Western Blot, IP
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: TRUE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 ug |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |