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Anti-FGF21 Antibody (Clone# ARC0865) | A2237
- SKU:
- 26-A2237-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
Fibroblast growth factor 21 (FGF21) is a pleiotropic hormone that belongs to the fibroblast growth factor family that has multifaceted roles in biological processes such as angiogenesis, metabolism, embryonic development, and tumor growth and invasion. FGF21 is expressed in multiple tissues such as the liver, adipose tissue, pancreas, brain, and gastrointestinal tract. FGF21 is known as a major regulator of glucose and lipid metabolism. Under nutritional stress conditions (fasting, caloric restriction, ketogenic diets), FGF21 stimulates the production of glucose in the liver via gluconeogenesis. In the adipose tissue, it increases the uptake of glucose by stimulating the expression of GLUT1. FGF21 promotes weight loss without decreasing the intake of food, decreases the fat content in the liver, and reduces triglyceride and glucose concentrations in the blood plasma. Due to its beneficial role in energy homeostasis and metabolism, FGF21 has been proposed as a therapeutic target for metabolic disorders.
A2237 | Anti-FGF21 Antibody (Clone# ARC0865) DataSheet
Antibody Target: FGF21
Target Alternative Name: Fibroblast Growth Factor 21, FGF-21, FGF21, FGF 21
Tag Line: Rabbit monoclonal antibody that detects the expression of FGF21 in human, mouse, and rat samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Rat,Mouse,Human
Immunogen Sequence: Synthetic peptide derived from human FGF21
Accession #: Q9NSA1
Gene ID: 26291
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH 7.3
Purification: Affinity purified
Application: Immunohistochemistry (IHC),Western Blotting
Positive Control:
Application And Usages: WB 1:500 - 1:2000, IHC 1:50 - 1:200
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: TRUE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 uL |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |