Anti-IL17RC Antibody | A1775

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling.

A1775 | Anti-IL17RC Antibody DataSheet

Antibody Target: Interleukin-17 receptor C

Target Alternative Name: IL 17 receptor C, IL 17RC, IL17RL, Interleukin 17 receptor C, Interleukin 17 receptor homolog, Interleukin 17 receptor like protein

Tag Line: Polyclonal antibody to detect IL17RC in Human samples.

Category: Immunology

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: Recombinant protein of human IL17RC

Accession #: Q8NAC3

Gene ID: 84818

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.3 mg/ml

Formulation: PBS with 0.05% sodium azide, 50% glycerol, PH7.3

Purification: Affinity purification

Application: Immunohistochemistry (IHC), ELISA

Positive Control:

Application And Usages: IHC 1:25-1:100

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: False

Immunocytochemistry Verified: False

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False