Anti- IL17RC Antibody | FNab04231

Anti- IL17RC Antibody | FNab04231 | Gentaur UK, US & Europe Distribution

Form: liquid

Purification: Immunogen affinity purified

Purity: ≥95% as determined by SDS-PAGE

Host: Rabbit

Clonality: polyclonal

Clone ID: N/A

Isotype: IgG

Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)

Background: Receptor for IL17A and IL17F homodimers as part of a heterodimeric complex with IL17RA (PubMed:16785495) . Receptor for the heterodimer formed by IL17A and IL17B as part of a heterodimeric complex with IL17RA (PubMed:18684971) . Has also been shown to be the cognate receptor for IL17F and to bind IL17A with high affinity without the need for IL17RA (PubMed:17911633) . Activation of IL17RC leads to induction of expression of inflammatory chemokines and cytokines such as CXCL1 (PubMed:16785495) . Isoform 5: Receptor for both IL17A and IL17F. Isoform 6: Does not bind IL17A or IL17F. Isoform 7: Does not bind IL17A or IL17F. Isoform 8: Receptor for both IL17A and IL17F.

Immunogen: interleukin 17 receptor C

synonyms: N/A

Molecular weight (observed) : 45-50kd

Reactivity Species: Human, Mouse

Tested Application: ELISA, WB, IHC, IF, IP

Recomended Dillution : WB: 1:500-1:2000

Research Area: Immunology, cancer