Anti-Laminin ?1 Antibody | A1244

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface.

A1244 | Anti-Laminin ?1 Antibody DataSheet

Antibody Target: LAMB1

Target Alternative Name: LAMB1; Laminin subunit beta-1; Laminin B1 chain; Laminin-1 subunit beta; Laminin-10 subunit beta; Laminin-12 subunit beta; Laminin-2 subunit beta; Laminin-6 subunit beta; Laminin-8 subunit beta

Tag Line: Polyclonal antibody to detect endogenous levels of Laminin ?1 protein in human and mouse

Category:

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse

Immunogen Sequence: Synthesized peptide derived from the C-terminal region of human Laminin ?-1 at AA range: 1690-1770

Accession #: P07942

Gene ID: 3912

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide

Purification: Affinity-chromatography using epitope-specific immunogen

Application: WB, IHC, IF, ELISA

Positive Control: WB: HepG2 cell lysate

Application And Usages: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:10000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans

Handling: The antibody solution should be gently mixed before use

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified: Not Verified

Flow Cytometry Verified: Not Verified