Anti-MART1 Rabbit Monoclonal Antibody (RM333) | A1845

MART-1 (also known as Melan-A) is a melanocyte differentiation antigen or marker recognized by autologous cytotoxic T lymphocytes. It is a membrane protein with one transmembrane peptide. Melan-A is expressed by a large proportion of melanoma tumors, both melanotic and amelanotic and by melanoma cell lines. It is present in melanocytes of normal skin and retina, nevi and in more than 85% of melanomas. Melan-A/MART-1 is not expressed by non-melanoma malignancies. It is recognized by autologous cytotoxic T lymphocytes. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. Six other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, Tyrosinase, gp100, gp75, BAGE-1, and GAGE-1.

A1845 | Anti-MART1 Rabbit Monoclonal Antibody (RM333) DataSheet

Antibody Target: MART-1 (Melanoma antigen recognized by T-cells 1)

Target Alternative Name:

Tag Line: Affinity purified Rabbit monoclonal to MART1

Category: Primary antibody

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: A peptide corresponding to the N-terminus of human MART1 (Melanoma antigen recognized by T-cells-1).

Accession #: Q16655

Gene ID: 2315

Appearance: Liquid

Form: Liquid

Concentration:

Formulation: 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide

Purification: Protein A affinity purified from an animal origin–free culture supernatant

Application: Western Blot: 1:500-1:1000, IHC: 1:500-1:1000

Positive Control:

Application And Usages: Western Blot: 1:500-1:1000, IHC: 1:500-1:1000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: True

Immunocytochemistry Verified: True

Immunofluorescence Verified: False

Immunoprecipitation Verified: False

FACS Verified: False

ELISA Verified: False

ChIP Verified: False

Dot Blot Verified: False

Flow Cytometry Verified: False