Anti-SARS-CoV-2 S1 Antibody (Clone# S309) | A2266

Coronaviruses (CoV) are a large group of enveloped positive-sense RNA viruses. They belong to subfamily Coronavirinae, in the family of Coronaviridae, of the order of Nidovirales. The Coronavirus genome is about 30 kb in length and encodes four structural proteins, namely, spike (S), envelope (E), membrane (M) and nucleocapsid (N), multiple nonstructural proteins, and other accessory proteins. The Spike (S) protein is a 180 kDa type I glycosylated transmembrane protein, that assembles as a trimer on the surface of the virus, hence the coronavirus appears crown-shaped (In Latin, corona means crown). The ectodomain of the Spike protein consists of two domains: the S1 domain whose main function is receptor binding, and the S2 domain whose main function is membrane fusion. S1 binds to the cell surface receptor of the host for attachment during the viral entry, this induces a conformational change in the S2, thus enabling the fusion of host and viral membranes and ultimately entry of the viral genome in the host cell.

A2266 | Anti-SARS-CoV-2 S1 Antibody (Clone# S309) DataSheet

Antibody Target: SARS-CoV-2 Spike S1

Target Alternative Name: Spike protein, COVID19, COVID 19, S protein, SARS-CoV S protein, S glycoprotein, E2, Peplomer protein, Spike protein S1, SARS Coronavirus, SARS-CoV-2, SARS CoV 2, 2019-nCoV, S309

Tag Line: Recombinant monoclonal antibody (Clone# S309) to detect SARS-CoV-2 Spike S1 protein

Category: Primary antibody

Host: Recombinant

Isotype: Human IgG1

Species Reactivities: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), SARS-CoV

Immunogen Sequence: Recombinant SARS-CoV-2 RBD protein

Accession #:

Gene ID:

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS, pH 7.5

Purification:

Application: ELISA

Positive Control:

Application And Usages: ELISA 1:5000-1:10,000

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: TRUE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE