Anti-SFTPD Antibody | A2253

Surfactant protein D is a 43 kDa glycoprotein that belongs to the family of collectins, which are a group of collagen-containing C-type lectins. The protein is synthesized and secreted by alveolar type II cells and non-ciliated airway cells. The gene for SP-D, SFTPD, is located on the long arm of the chromosome 10q22.2-23.1. SFTPD plays a significant role in innate immune response and protects the lungs from inhaled microorganisms, toxins, and organic antigens. It binds to a variety of phospholipids, polysaccharides, and glycolipids located on the surface of bacteria, viruses, and allergens and promote the killing of these pathogens by phagocytosis. Increased levels of SP-D are associated with the development, progression, and severity of pulmonary diseases such as COPD, idiopathic pulmonary fibrosis, and acute respiratory distress syndrome (ARDS). Therefore it is considered a promising biomarker for lung inflammation and pulmonary diseases

A2253 | Anti-SFTPD Antibody DataSheet

Antibody Target: SFTPD

Target Alternative Name: SP-D, PSP-D, SFTP4, COLEC7, SFTPD

Tag Line: Rabbit polyclonal antibody to detect Surfactant Protein D (SFTPD) in human samples

Category: Primary antibody

Host: Rabbit

Isotype: IgG

Species Reactivities: Human

Immunogen Sequence: Fusion protein of Human SFTPD

Accession #: P35247

Gene ID: 6441

Appearance: Colorless liquid

Form: Liquid

Concentration:

Formulation: In PBS, pH 7.4, 40% glycerol, 0.05% sodium azide

Purification: Antigen Affinity purified

Application: Immunohistochemistry (IHC)

Positive Control:

Application And Usages: IHC 1:25-1:100

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: FALSE

Immunocytochemistry Verified: FALSE

Immunofluorescence Verified: FALSE

Immunoprecipitation Verified: FALSE

FACS Verified: FALSE

ELISA Verified: FALSE

ChIP Verified: FALSE

Dot Blot Verified: FALSE

Flow Cytometry Verified: FALSE