26
Anti-SFTPD Antibody | A2253
- SKU:
- 26-A2253-100-GEN
- Availability:
- Usually shipped in 5 working days
Description
Surfactant protein D is a 43 kDa glycoprotein that belongs to the family of collectins, which are a group of collagen-containing C-type lectins. The protein is synthesized and secreted by alveolar type II cells and non-ciliated airway cells. The gene for SP-D, SFTPD, is located on the long arm of the chromosome 10q22.2-23.1. SFTPD plays a significant role in innate immune response and protects the lungs from inhaled microorganisms, toxins, and organic antigens. It binds to a variety of phospholipids, polysaccharides, and glycolipids located on the surface of bacteria, viruses, and allergens and promote the killing of these pathogens by phagocytosis. Increased levels of SP-D are associated with the development, progression, and severity of pulmonary diseases such as COPD, idiopathic pulmonary fibrosis, and acute respiratory distress syndrome (ARDS). Therefore it is considered a promising biomarker for lung inflammation and pulmonary diseases
A2253 | Anti-SFTPD Antibody DataSheet
Antibody Target: SFTPD
Target Alternative Name: SP-D, PSP-D, SFTP4, COLEC7, SFTPD
Tag Line: Rabbit polyclonal antibody to detect Surfactant Protein D (SFTPD) in human samples
Category: Primary antibody
Host: Rabbit
Isotype: IgG
Species Reactivities: Human
Immunogen Sequence: Fusion protein of Human SFTPD
Accession #: P35247
Gene ID: 6441
Appearance: Colorless liquid
Form: Liquid
Concentration:
Formulation: In PBS, pH 7.4, 40% glycerol, 0.05% sodium azide
Purification: Antigen Affinity purified
Application: Immunohistochemistry (IHC)
Positive Control:
Application And Usages: IHC 1:25-1:100
Country of Animal Origin: USA
Country of Manufacture: USA
Usage: For Research Use Only! Not to be used in humans.
Handling: The antibody solution should be gently mixed before use.
Western Blot Verified: FALSE
Immunocytochemistry Verified: FALSE
Immunofluorescence Verified: FALSE
Immunoprecipitation Verified: FALSE
FACS Verified: FALSE
ELISA Verified: FALSE
ChIP Verified: FALSE
Dot Blot Verified: FALSE
Flow Cytometry Verified: FALSE
Additional Information
Size: |
100 uL |
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |