BMP4 Antibody| F45385-0.08ML/F45385-0.4ML/R31950

BMP4 Antibody| F45385-0.08ML/F45385-0.4ML/R31950 | Gentaur UK, US & Europe Distribution

Background: Bmp4 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. This particular family member plays an important role in the onset of endochondral bone formation in humans, and a reduction in expression has been associated with a variety of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Alternative splicing in the 5' untranslated region of this gene has been described and three variants are described, all encoding an identical protein.

Format: Purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Mouse, Bovine, Rabbit

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the BMP4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This BMP4 antibody is available for research use only.

Purity: Purified

Immunogen: A portion of amino acids 5-34 from the human protein was used as the immunogen for this BMP4 antibody.

Storage: Aliquot the BMP4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A