CD86 Antibody| F44504-0.08ML/F44504-0.4ML/R30465/V2056-20UG/V2056FITC-100T/V2056IHC-7ML

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CD86 Antibody| F44504-0.08ML/F44504-0.4ML/R30465/V2056-20UG/V2056FITC-100T/V2056IHC-7ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in two transcript variants encoding different isoforms. Additional transcript variants have been described, but their full-length sequences have not been determined. [provided by RefSeq].

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the CD86 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD86 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 269-298 from the human protein was used as the immunogen for this CD86 antibody.

Storage: Aliquot the CD86 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A

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