CDY2B Antibody | 14-571

CDY2B Antibody | 14-571 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human CDY2B (NP_001001722.1) .

Research Area: Other

Tested Application: WB

Application: WB: 1:1000 - 1:3000

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: Mouse kidney

Positive Control 3: Rat kidney

Positive Control 4: Rat liver

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 60kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDY, testis-specific chromodomain protein Y 2, Y chromosome chromodomain protein 2B, chromodomain protein, Y chromosome, 2 related, chromodomain protein, Y-linked, 2B, testis-specific chromodomain protein Y protein 2 related

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This intronless gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. Two nearly identical copies of this gene are found in a palindromic region on chromosome Y; this record represents the centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes.