CXCR4 Antibody | 5541

CXCR4 (fusin) is a member in the seven-transmembrane domain G-protein-coupled chemokine receptor family. The full-length cDNA was isolated from a human spleen cDNA library. Its ligand is chemokine stroma-derived factor (SDF). CXCR4 has been shown to be the co-receptor for HIV-1 binding to CD4 thro?gh the viral envelope glycoprotein gp120. In other cases, CXCR4 can function as the only receptor for the interaction of HIV-2 with CD4 and host cells. A mouse monoclonal antibody (12G5) to CXCR4 has been shown to inhibit HIV infectivity and HIV-induced syncytium.

5541 | CXCR4 Antibody DataSheet

Antibody Target: CXCR4

Target Alternative Name: chemokine C-X-C motif receptor 4, chemokine receptor 4

Tag Line:

Category: CXCR4

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse, rat

Immunogen Sequence: Synthetic peptide surrounding amino acid 18 of mouse CXCR4

Accession #: P70658

Gene ID: 12767

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) affinity purified rabbit anti-CXCR4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Purification: Affinity purified

Application: Western blot

Positive Control:

Application And Usages: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (Cat.# 5541BP-50) is available separately.

Country of Animal Origin: China

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified: Not Verified

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified