F2 Antibody | XW-7706

F2 Antibody | XW-7706 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Human

Homology: N/A

Immunogen: 1-622

Research Area: Other

Tested Application: WB

Application: Prothrombin antibody can be used for the detection of Prothrombin by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 70 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: F2 antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: Prothrombin, Coagulation factor II, Prothrombin

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C.

DISEASE: Defects in F2 are the cause of various forms of dysprothrombinemia [MIM:176930].

CATALYTIC ACTIVITY: Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.