GSK-2982772 | B2232

GSK-2982772 is a potent and ATP-competitive receptor-interacting protein-1 (RIP1) kinase inhibitor (IC₅₀ = 1 nM).

GSK-2982772 is a potent and ATP-competitive receptor-interacting protein-1 (RIP1) kinase inhibitor (IC₅₀ = 1 nM).

B2232 | GSK-2982772 DataSheet

Alternate Name/Synonyms: 5-benzyl-N-[(3S)-5-methyl-4-oxo-2,3-dihydro-1,5-benzoxazepin-3-yl]-1H-1,2,4-triazole-3-carboxamide

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1622848-92-3

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₁₉N₅O₃

Molecular Weight: 377.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent and ATP-competitive receptor-interacting protein-1 (RIP1) kinase inhibitor

MDL Number: N/A

PubChem CID: 77108121

SMILES: CN1C2=CC=CC=C2OCC(C1=O)NC(=O)C3=NNC(=N3)CC4=CC=CC=C4

InChi: InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14-/m0/s1

InChi Key: LYPAFUINURXJSG-AWEZNQCLSA-N