Human Recombinant SORD | 6388

SORD, also known as L-iditol 2-dehydrogenase or SORD1, is a 357 amino acid member of the zinc containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney and in the lens of the eye. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses.

6388 | Human Recombinant SORD DataSheet

Biomolecule/Target: N/A

Synonyms: Human Recombinant SORD

Alternates names: Sorbitol dehydrogenase

Taglines: Catalyzes the Zn-dependent interconversion of polyols

NCBI Gene ID #: 3606

NCBI Gene Symbol: IL18

Gene Source: Human

Accession #: Q14116

Recombinant: Yes

Source: E. Coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Specific activity is > 0.2 units/mg

Results: >0.2 units/mg

Binding Capacity: N/A

Unit Definition: One unit will convert 1.0 µmole of D-fructose to D-sorbitol per minute at pH 7.5 at 25°C.

Molecular Weight: 40.4 kDa (377 aa, 1-357 aa + NT His Tag)

Concentration: 0.5 mg/ml

Appearance: Liquid

Physical form description: 0.5 mg/ml solution in 20 mM Tris-HCl buffer (pH 8.0) containing 0.2 M NaCl, 5 mM DTT and 20% glycerol.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MAAAAKPNNL SLVVHGPGDL RLENYPIPEP GPNEVLLRMH SVGICGSDVH YWEYGRIGNF IVKKPMVLGH EASGTVEKVG SSVKHLKPGD RVAIEPGAPR ENDEFCKMGR YNLSPSIFFC ATPPDDGNLC RFYKHNAAFC YKLPDNVTFE EGALIEPLSV GIHACRRGGV TLGHKVLVCG AGPIGMVTLL VAKAMGAAQV VVTDLSATRL SKAKEIGADL VLQISKESPQ EIARKVEGQL GCKPEVTIEC TGAEASIQAG IYATRSGGTL VLVGLGSEMT TVPLLHAAIR EVDIKGVFRY CNTWPVAISM LASKSVNVKP LVTHRFPLEK ALEAFETFKK GLGLKIMLKC DPSDQNP