749
Myosin Heavy Chain Monoclonal Antibody | ABM40058
- SKU:
- 749-ABM40058
- Availability:
- Usually ships in 5 working days
Description
Myosin Heavy Chain Monoclonal Antibody | ABM40058 | Gentaur UK, US & Europe Distribution
Immunogen: Synthetic Peptide
Product Category: Protein
Application: Protein General Reagents
Product Type: Primary Antibody
Host: Mouse
Reactivity: Human, Mouse, Rat, Fruit Fly, Nematode
Application: IF
Application Note: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IF (1:100) .
Clonality: Monoclonal
Isotype: Mouse IgG1
Formulation: Liquid solution
Kit Component: N/A
Concentration: 1 mg/ml
Storage Buffer: PBS, pH 7.4, containing 0.02% Sodium Azide as preservative and 50% Glycerol.
Storage Instructions: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Shipping Condition: Gel pack with blue ice.
Background: Skeletal muscle Myosin or myosin II is the motor protein that generates force to drive muscle contraction. It is a 520 kDa hexamer comprised of two heavy chains and four light chains. Myosin heavy chain is 220 kDa in size and consists of a long coiled-coil domain tail that mediates dimerization of the two heavy chains and a globular head region that mediates ATP-dependent sliding of actin filaments. Myosin heavy chain can be proteolytically cleaved to produce heavy meromyosin, which includes the S1 motor domain (head region) and first third of the coiled coil domain, and light meromyosin, which includes the C-terminal two thirds of the coiled coil domain.
Alternative Names: Myosin Heavy Chain
Precaution: The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.