PIK3CG monoclonal Antibody | MB64497

PIK3CG monoclonal Antibody | MB64497 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Application: WB

Application Range: WB 1:1000

Background: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. [provided by RefSeq, Jul 2008]

Storage & Stability: PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Specificity: phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma

Molecular Weight: 126.3 kDa (Predicted)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3

Immunogen: Full length human recombinant protein of human PIK3CG (NP_002640) produced in HEK293T cell.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G)

Pathway: N/A