Polymyxin B sulfate | 2496

Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram negative bacteria leading to lysing of the cell. Polymyxin B only needs to interact with LPS, it is not required to enter the cell. Polymyxin B is routinely used as a selection agent in several types of isolation media.

Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram negative bacteria leading to lysing of the cell.

2496 | Polymyxin B sulfate DataSheet

Alternate Name/Synonyms: Aerosporin; Mastimyxin

Appearance: White solid

Formulation: N/A

CAS Number: 1405-20-5

Structure Available?: No

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₅₅H₉₆N₁₆O₁₃ · 2H₂SO₄

Molecular Weight: 1385.61

Cell-Permeable?: No

Purity: >6000 units/mg

Solubilities: H₂O (25 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: An antibiotic and selection agent

MDL Number: MFCD00131991

PubChem CID: 5702105

SMILES: CCC(C)CCCCC(=O)NC(CCN)C(=O)NC(C(C)O)C(=O)NC(CCN)C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCN)CC2=CC=CC=C2)CC(C)C)CCN)CCN)C(C)O.OS(=O)(=O)O

InChi: InChI=1S/C56H98N16O13.H2O4S/c1-7-32(4)13-11-12-16-44(75)63-36(17-23-57)51(80)72-46(34(6)74)56(85)68-39(20-26-60)48(77)67-41-22-28-62-55(84)45(33(5)73)71-52(81)40(21-27-61)65-47(76)37(18-24-58)66-53(82)42(29-31(2)3)69-54(83)43(30-35-14-9-8-10-15-35)70-49(78)38(19-25-59)64-50(41)79;1-5(2,3)4/h8-10,14-15,31-34,36-43,45-46,73-74H,7,11-13,16-30,57-61H2,1-6H3,(H,62,84)(H,63,75)(H,64,79)(H,65,76)(H,66,82)(H,67,77)(H,68,85)(H,69,83)(H,70,78)(H,71,81)(H,72,80);(H2,1,2,3,4)

InChi Key: HFMDLUQUEXNBOP-UHFFFAOYSA-N