Description
Cell-permeable. A dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀= 31.9 µM) in transfected COS-7 cells.
PPARγ Antagonist, G3335 is a dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀= 31.9 µM) in transfected COS-7 cells.
1979 | PPARγ Antagonist, G3335 DataSheet
Alternate Name/Synonyms: G3335; H-Trp-Glu-OH
Appearance: White solid
Formulation: N/A
CAS Number: 36099-95-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₆H₁₉N₃O₅
Molecular Weight: 333.34
Cell-Permeable?: Yes
Purity: ≥97% by elemental analysis
Solubilities: Water
Handling: Protect from light and mositure
Country of Origin: USA
Tag Line: A selective and reversible PPARγ antagonis
MDL Number: MFCD00037964
PubChem CID: 3634442
SMILES: C1=CC=C2C(=C1)C(=CN2)CC(C(=O)NC(CCC(=O)O)C(=O)O)N
InChi: InChI=1S/C16H19N3O5/c17-11(7-9-8-18-12-4-2-1-3-10(9)12)15(22)19-13(16 (23)24)5-6-14(20)21/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23, 24)
InChi Key: PWIQCLSQVQBOQV-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
60 months |