Description
Isolated from Serratia marcescens. Displays antibacterial, anticancer, cytotoxic, immunosuppressive, and antiproliferative activities. Prodigiosin induces apoptosis in hematopoietic cancer cells and cells derived from other human cancers, including gastric and colon with no marked toxicity in nonmalignant cell lines. Also acts as a mTORC1 and mTORC2 complex inhibitor.
Prodigiosin displays antibacterial, anticancer, cytotoxic, immunosuppressive, and antiproliferative activities. Also acts as a mTORC1 and mTORC2 complex inhibitor.
Alternate Name/Synonyms: 4-methoxy-5-[(Z)-(5-methyl-4-pentyl-2H-pyrrol-2-ylidene)methyl]-1H,1′H-2,2′-bipyrrole; NSC 47147; BRN 4526727
Appearance: Dark red solid
Formulation: N/A
CAS Number: 82-89-3
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₅N₃O
Molecular Weight: 323.43
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO or Ethanol
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A mTORC1 and mTORC2 complex inhibitor.
MDL Number: N/A
PubChem CID: 5351169
SMILES: CCCCCC1=C(NC(=C1)C=C2C(=CC(=C3C=CC=N3)N2)OC)C
InChi: InChI=1S/C20H25N3O/c1-4-5-6-8-15-11-16(22-14(15)2)12-19-20(24-3)13-18(23-19)17-9-7-10-21-17/h7,9-13,22-23H,4-6,8H2,1-3H3/b18-17-,19-12-
InChi Key: WKGQSEFBQTWRPT-UUPRNIFOSA-N
Additional Information
Storage Condition: |
-20 ̊C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |