PU-WS13 | 9442

PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 has been shown to reduce the viability of breast cancer cells that express high levels of cell surface HER2 and the viability of human multiple myeloma cells in vitro.

PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 has been shown to reduce the viability of breast cancer cells that express high levels of cell surface HER2 and the viability of human multiple myeloma cells in vitro.

9442 | PU-WS13 DataSheet

Alternate Name/Synonyms: 8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine

Appearance: White solid

Formulation: N/A

CAS Number: 1454619-14-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₇H₂₀Cl₂N₆S

Molecular Weight: 411.35

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class

MDL Number: N/A

PubChem CID: 71660551

SMILES: CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=CC(=CC(=C3)Cl)Cl

InChi: InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-16-14(15(20)22-9-23-16)24-17(25)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5H2,1-2H3,(H2,20,22,23)

InChi Key: JYSLFQTWNRYWJT-UHFFFAOYSA-N