Description
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 has been shown to reduce the viability of breast cancer cells that express high levels of cell surface HER2 and the viability of human multiple myeloma cells in vitro.
PU-WS13 is a potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class. PU-WS13 has been shown to reduce the viability of breast cancer cells that express high levels of cell surface HER2 and the viability of human multiple myeloma cells in vitro.
Alternate Name/Synonyms: 8-((3,5-Dichlorophenyl)thio)-9-(3-(isopropylamino)propyl)-9H-purin-6-amine
Appearance: White solid
Formulation: N/A
CAS Number: 1454619-14-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₂₀Cl₂N₆S
Molecular Weight: 411.35
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent, Grp94-specific Hsp90 inhibitor of the purine scaffold class
MDL Number: N/A
PubChem CID: 71660551
SMILES: CC(C)NCCCN1C2=C(C(=NC=N2)N)N=C1SC3=CC(=CC(=C3)Cl)Cl
InChi: InChI=1S/C17H20Cl2N6S/c1-10(2)21-4-3-5-25-16-14(15(20)22-9-23-16)24-17(25)26-13-7-11(18)6-12(19)8-13/h6-10,21H,3-5H2,1-2H3,(H2,20,22,23)
InChi Key: JYSLFQTWNRYWJT-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |