Purmorphamine | 1672

A 2,6,9-trisubstituted purine that promotes the differentiation of both human and murine mesenchymal progenitor cells into osteoblasts. It directly binds to and activates 7-transmembrane Smo receptor of the Hedgehog (Hh) signaling pathway.

Purmorphamine is a 2,6,9-trisubstituted purine that promotes the differentiation of both human and murine mesenchymal progenitor cells into osteoblasts. It directly binds to and activates 7-transmembrane Smo receptor of the Hedgehog (Hh) signaling pathway.

1672 | Purmorphamine DataSheet

Alternate Name/Synonyms: 9-cyclohexyl-N-(4-morpholin-4-ylphenyl)-2-naphthalen-1-yloxypurin-6-amine

Appearance: Off-white solid

Formulation: N/A

CAS Number: 483367-10-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₁H₃₂N₆O₂

Molecular Weight: 520.62

Cell-Permeable?: Yes

Purity: ≥98% by TLC

Solubilities: DMSO (200 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A stem cell differentiating agent

MDL Number: N/A

PubChem CID: 5284329

SMILES: FYBHCRQFSFYWPY-UHFFFAOYSA-N

InChi: InChI=1S/C31H32N6O2/c1-2-9-25(10-3-1)37-21-32-28-29(33-23-13-15-24(16-14-23)36-17-19-38-20-18-36)34-31(35-30(28)37)39-27-12-6-8-22-7-4-5-11-26(22)27/h4-8,11-16,21,25H,1-3,9-10,17-20H2,(H,33,34,35)

InChi Key: C1CCC(CC1)N2C=NC3=C2N=C(N=C3NC4=CC=C(C=C4)N5CCOCC5)OC6=CC=CC7=CC=CC=C76