Pyridoclax | B1817

Pyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM). Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.

Pyridoclax(MR-29072) is a potent Mcl-1 inhibitor (Kd = 25 nM). Pyridoclax is able to disrupt BimL/Mcl-1 interaction in whole living cells.

B1817 | Pyridoclax DataSheet

Alternate Name/Synonyms: (E)-3'-methyl-3''-styryl-3,2':5',2'':5'',3'''-quaterpyridine; MR29072

Appearance: Crystalline solid

Formulation: N/A

CAS Number: 1651890-44-6

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: N/A

Molecular Formula: C₂₉H₂₂N₄

Molecular Weight: 426.51

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent Mcl-1 inhibitor

MDL Number: N/A

PubChem CID: 92042827

SMILES: CC1=C(N=CC(=C1)C2=C(C=C(C=N2)C3=CN=CC=C3)C=CC4=CC=CC=C4)C5=CN=CC=C5

InChi: InChI=1S/C29H22N4/c1-21-15-27(20-32-28(21)25-10-6-14-31-18-25)29-23(12-11-22-7-3-2-4-8-22)16-26(19-33-29)24-9-5-13-30-17-24/h2-20H,1H3/b12-11+

InChi Key: WGGSYXQFYRWBEC-VAWYXSNFSA-N