Pyroxamide | 2189

Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.

Pyroxamide is a potent inhibitor of histone deacetylase 1 (HDAC1) (IC₅₀ = 100 nM). It induces growth suppression and cell death of certain types of cancer cells in culture.

2189 | Pyroxamide DataSheet

Alternate Name/Synonyms: N1-​hydroxy-​N8-​3-​pyridinyl-​octanediamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 382180-17-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₁₃H₁₉N₃O₃

Molecular Weight: 265.31

Cell-Permeable?: Yes

Purity: ≥95%

Solubilities: DMSO (~ 10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A potent HDAC1 inhibitor

MDL Number: MFCD13194970

PubChem CID: 4996

SMILES: C1=CC(=CN=C1)NC(=O)CCCCCCC(=O)NO

InChi: InChI=1S/C13H19N3O3/c17-12(15-11-6-5-9-14-10-11)7-3-1-2-4-8-13(18)16-19/h5-6,9-10,19H,1-4,7-8H2,(H,15,17)(H,16,18)

InChi Key: PTJGLFIIZFVFJV-UHFFFAOYSA-N