QS11 | 1680

Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/β-catenin signaling pathway. The Wnt/β-catenin signaling pathway regulates cell fate and behavior during embryogenesis, adult tissue homeostasis, and regeneration.

QS11 Inhibits the GTPase activating protein of ADP-ribosylation factor 1 (ARFGAP1) as well as synergizes the Wnt/β-catenin signaling pathway.

1680 | QS11 DataSheet

Alternate Name/Synonyms: (2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol

Appearance: White solid

Formulation: N/A

CAS Number: 944328-88-5

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₃₆H₃₃N₅O₂

Molecular Weight: 567.68

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (>10 mg/ml)

Handling: Protect from air and moisture

Country of Origin: USA

Tag Line: A stem cell fate regulator

MDL Number: MFCD12912439

PubChem CID: 42623900

SMILES: C1CC2=C(C1)C=C(C=C2)OC3=NC4=C(C(=N3)NC(CC5=CC=CC=C5)CO)N=CN4CC6=CC=C(C=C6)C7=CC=CC=C7

InChi: InChI=1S/C36H33N5O2/c42-23-31(20-25-8-3-1-4-9-25)38-34-33-35(40-36(39-34)43-32-19-18-28-12-7-13-30(28)21-32)41(24-37-33)22-26-14-16-29(17-15-26)27-10-5-2-6-11-27/h1-6,8-11,14-19,21,24,31,42H,7,12-13,20,22-23H2,(H,38,39,40)/t31-/m0/s1

InChi Key: DOKZLKDGUQWMSX-HKBQPEDESA-N