Qstatin | B2618

Qstatin is a potent, and selective Vibrio QS inhibitor which affects Vibrio harveyi LuxR homologues, the well-conserved master transcriptional regulators for QS in Vibrio species. QStatin binds tightly to a putative ligand-binding pocket in SmcR, the LuxR homologue in V. vulnificus, and changes the flexibility of the protein, thereby altering its transcription regulatory activity.

Qstatin is a potent, and selective Vibrio QS inhibitor which affects Vibrio harveyi LuxR homologues, the well-conserved master transcriptional regulators for QS in Vibrio species. QStatin binds tightly to a putative ligand-binding pocket in SmcR, the LuxR homologue in V. vulnificus, and changes the flexibility of the protein, thereby altering its transcription regulatory activity.

B2618 | Qstatin DataSheet

Alternate Name/Synonyms: 1-(5-Bromothiophene-2-sulfonyl)-1H-pyrazole, Q-statin

Appearance: Crystalline solid

Formulation:

CAS Number: 902688-24-8

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₇H₅BrN₂O₂S₂

Molecular Weight: 293.15

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Qstatin is a potent and selective inhibitor of quorum sensing (QS) in vibrio species

MDL Number:

PubChem CID: 3237735

SMILES: O=S(N1N=CC=C1)(C2=CC=C(Br)S2)=O

InChi: InChI=1S/C7H5BrN2O2S2/c8-6-2-3-7(13-6)14(11,12)10-5-1-4-9-10/h1-5H

InChi Key: MLRBBGFHILYDBK-UHFFFAOYSA-N