Description
Rasfonin, isolated from Talaromyces sp., is a selective apoptosis inducer in ras-dependent cells. Rasfonin induces autophagy concomitant with upregulation of Akt phosphorylation.
Rasfonin, isolated from Talaromyces sp., is a selective apoptosis inducer in ras-dependent cells. Rasfonin induces autophagy concomitant with upregulation of Akt phosphorylation.
Alternate Name/Synonyms: [(2R,3R)-2-[(E,2S,4R)-4,6-dimethyloct-6-en-2-yl]-6-oxo-2,3-dihydropyran-3-yl] (2E,4E,6S)-8-hydroxy-6-(hydroxymethyl)-4-methylocta-2,4-dienoate
Appearance: Tan to brown viscous liquid
Formulation: N/A
CAS Number: 303156-68-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₅H₃₈O₆
Molecular Weight: 434.57
Cell-Permeable?: Yes
Purity: ≥95% by HPLC
Solubilities: DMSO (~ 1 mg/ml) or EtOH (~ 1 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An apoptosis and autophagy inducer
MDL Number: N/A
PubChem CID: 11259090
SMILES: CC=C(C)CC(C)CC(C)C1C(C=CC(=O)O1)OC(=O)C=CC(=CC(CCO)CO)C
InChi: InChI=1S/C25H38O6/c1-6-17(2)13-19(4)14-20(5)25-22(8-10-24(29)31-25)30-23(28)9-7-18(3)15-21(16-27)11-12-26/h6-10,15,19-22,25-27H,11-14,16H2,1-5H3/b9-7+,17-6+,18-15+/t19-,20-,21-,22+,25+/m0/s1
InChi Key: OHRGHFXATDKGOV-FXYCKZMJSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |