RBBP4 Antibody | 15-274

RBBP4 Antibody | 15-274 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-425 of human RBBP4 (NP_005601.1) .

Research Area: Cancer, Cell Cycle

Tested Application: WB, IF, ChIP

Application: WB: 1:500 - 1:2000
IF: 1:50 - 1:200
ChIP: 1:20 - 1:50

Specificiy: N/A

Positive Control 1: SW480

Positive Control 2: HeLa

Positive Control 3: Jurkat

Positive Control 4: 293T

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 48kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: RBAP48, Histone-binding protein RBBP4, Chromatin assembly factor 1 subunit C, CAF-1 subunit C, NURF55

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.