Description
RG7834 is a highly selective and orally bioavailable HBV (Hepatitis B Virus) inhibitor, that potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.
RG7834 is a highly selective and orally bioavailable HBV (Hepatitis B Virus) inhibitor, that potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC₅₀s of 2.8, 2.6, and 3.2 nM, respectively, in dHepaRG Cells.
Alternate Name/Synonyms: RO7020322,(6S)-6-Isopropyl-10-methoxy-9-(3-methoxypropoxy)-2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid,RG-7834
Appearance: White to off-white solid
Formulation:
CAS Number: 2072057-17-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₇NO₆
Molecular Weight: 401.46
Cell-Permeable?: TRUE
Purity: ≥98%
Solubilities: >50 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A highly selective and orally bioavailable HBV inhibitor
MDL Number:
PubChem CID: 118261815
SMILES: CC(C)C1CC2=CC(=C(C=C2C3=CC(=O)C(=CN13)C(=O)O)OC)OCCCOC
InChi: InChI=1S/C22H27NO6/c1-13(2)17-8-14-9-21(29-7-5-6-27-3)20(28-4)10-15(14)18-11-19(24)16(22(25)26)12-23(17)18/h9-13,17H,5-8H2,1-4H3,(H,25,26)/t17-/m0/s1
InChi Key: KBXLMOYQNDMHQT-KRWDZBQOSA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |