Riviciclib hydrochloride | B2567

Riviciclib hydrochloride is a potent cyclin dependent kinase (CDK) inhibitor (IC₅₀ values of 79 nM, 63 nM and 20 nM for CDK1, CDK4 and CDK9, respectively). Displays potential antineoplastic activity.

Riviciclib hydrochloride is a potent cyclin dependent kinase (CDK) inhibitor (IC₅₀ values of 79 nM, 63 nM and 20 nM for CDK1, CDK4 and CDK9, respectively). Displays potential antineoplastic activity.

B2567 | Riviciclib hydrochloride DataSheet

Alternate Name/Synonyms: P27600, 2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)-4H-chromen-4-one hydrochloride, P 276-00, P276-00, Riviciclib

Appearance: Crystalline solid

Formulation:

CAS Number: 920113-03-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₁H₂₁Cl₂NO₅

Molecular Weight: 438.3

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent cyclin dependent kinase (CDK) inhibitor

MDL Number:

PubChem CID: 23643975

SMILES: CN1CCC(C1CO)C2=C(C=C(C3=C2OC(=CC3=O)C4=CC=CC=C4Cl)O)O.Cl

InChi: InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28-21(19)20)11-4-2-3-5-13(11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12-,14+;/m1./s1

InChi Key: OOVTUOCTLAERQD-OJMBIDBESA-N