Rogaratinib | B2638

Rogaratinib (BAY-1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor.

Rogaratinib (BAY-1163877) is a potent and selective fibroblast growth factor receptor (FGFR) inhibitor.

B2638 | Rogaratinib DataSheet

Alternate Name/Synonyms: BAY 1163877; 4-((4-amino-5-(7-methoxy-5-methylbenzo[b]thiophen-2-yl)-6-(methoxymethyl)pyrrolo[2,1-f][1,2,4]triazin-7-yl)methyl)piperazin-2-one; BAY1163877; BAY-1163877

Appearance: Crystalline solid

Formulation:

CAS Number: 1443530-05-9

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₃H₂₆N₆O₃S

Molecular Weight: 466.56

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: >5 mg/ml in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: A potent and selective fibroblast growth factor receptor (FGFR) inhibitor

MDL Number:

PubChem CID: 71611869

SMILES: CC1=CC2=C(C(=C1)OC)SC(=C2)C3=C4C(=NC=NN4C(=C3COC)CN5CCNC(=O)C5)N

InChi: InChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8,12H,4-5,9-11H2,1-3H3,(H,25,30)(H2,24,26,27)

InChi Key: HNLRRJSKGXOYNO-UHFFFAOYSA-N