RVX-208 | 9408

RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.

RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.

9408 | RVX-208 DataSheet

Alternate Name/Synonyms: 2-​[4-​(2-​hydroxyethoxy)-​3,​5-​dimethylphenyl]-​5,​7-​dimethoxy-​4(3H)-​quinazolinone

Appearance: Off-white solid

Formulation: N/A

CAS Number: 1044870-39-4

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₀H₂₂N₂O₅

Molecular Weight: 370.4

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 50 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A potent BET bromodomain inhibitor

MDL Number: N/A

PubChem CID: 24871506

SMILES: CC1=CC(=CC(=C1OCCO)C)C2=NC(=O)C3=C(C=C(C=C3N2)OC)OC

InChi: InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-

InChi Key: NETXMUIMUZJUTB-UHFFFAOYSA-N