Description
RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.
RVX-208 is a potent inhibitor of BET bromodomains. It increases apolipoprotein A-I and high-density lipoprotein cholesterol in vitro and in vivo.
Alternate Name/Synonyms: 2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinazolinone
Appearance: Off-white solid
Formulation: N/A
CAS Number: 1044870-39-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₀H₂₂N₂O₅
Molecular Weight: 370.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (~ 50 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent BET bromodomain inhibitor
MDL Number: N/A
PubChem CID: 24871506
SMILES: CC1=CC(=CC(=C1OCCO)C)C2=NC(=O)C3=C(C=C(C=C3N2)OC)OC
InChi: InChI=1S/C20H22N2O5/c1-11-7-13(8-12(2)18(11)27-6-5-23)19-21-15-9-
InChi Key: NETXMUIMUZJUTB-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |