S0859 | 9425

S0859 is a selective high-affinity generic inhibitor of the Na⁺/HCO3- sodium bicarbonate co-transporter (NBC). S0859 does not inhibit Na⁺-H⁺ exchange (NHE). S0859 could be potentially important for probing the transporter's functional role in heart and other tissues.

S0859 is a selective high-affinity generic inhibitor of the Na⁺/HCO3- sodium bicarbonate co-transporter (NBC). S0859 does not inhibit Na⁺-H⁺ exchange (NHE). S0859 could be potentially important for probing the transporter's functional role in heart and other tissues.

9425 | S0859 DataSheet

Alternate Name/Synonyms: (2-Chloro-N-[[2′-[(cyanoamino)sulfonyl][1,1′-biphenyl]-4-yl]methyl]-N-[(4-methylphenyl)methyl]-benzamide

Appearance: White to off-white solid

Formulation: N/A

CAS Number: 1019331-10-2

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₉H₂₄ClN₃O₃S

Molecular Weight: 530.04

Cell-Permeable?: Yes

Purity: ≥98% by HPLC

Solubilities: DMSO (~ 10 mg/ml)

Handling: Protect from air and light

Country of Origin: USA

Tag Line: A Na⁺/HCO3- sodium bicarbonate co-transporter (NBC) inhibitor

MDL Number: N/A

PubChem CID: 70675849

SMILES: CC1=CC=C(C=C1)CN(CC2=CC=C(C=C2)C3=CC=CC=C3S(=O)(=O)NC#N)C(=O)C4=CC=CC=C4Cl

InChi: InChI=1S/C29H24ClN3O3S/c1-21-10-12-22(13-11-21)18-33(29(34)26-7-2-4-8-27(26)30)19-23-14-16-24(17-15-23)25-6-3-5-9-28(25)37(35,36)32-20-31/h2-17,32H,18-19H2,1H3

InChi Key: ITDBPOSLOROLMT-UHFFFAOYSA-N