SAE1 Antibody | 5749

SAE1 Antibody | 5749 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: Predicted species reactivity based on immunogen sequence: Bovine: (90%)

Immunogen: SAE1 antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SAE1.
The immunogen is located within amino acids 240 - 290 of SAE1.

Research Area: Homeostasis

Tested Application: E, WB

Application: SAE1 antibody can be used for detection of SAE1 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested.

Specificiy: N/A

Positive Control 1: Cat. No. 1220 - SK-N-SH Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Predicted: 38 kDa
Observed: 39 kDa

Validation: N/A

Isoform: N/A

Purification: SAE1 Antibody is affinity chromatography purified via peptide column.

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: SAE1 Antibody is supplied in PBS containing 0.02% sodium azide.

Concentration: 1 mg/mL

Storage Condition: SAE1 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: SAE1 Antibody: AOS1, SUA1, UBLE1A, HSPC140, AOS1, SUMO-activating enzyme subunit 1, Ubiquitin-like 1-activating enzyme E1A

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: SAE1 Antibody: Small ubiquitin-like modifiers (SUMOs) are a family of small, related proteins (SUMO-1/2/3/4) that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation, a major regulator of protein function in cellular processes such as nuclear transport, transcriptional regulation, apoptosis and protein stability. This sumoylation is effected by the heterodimeric enzyme SAE1/SAE2 and the SUMO-1-conjugating enzyme Ubch9. The sumoylation pathway mediated by SAE1/SAE2 is distinct from other ubiquitin-like protein (Ubl) pathways.